DHFR

Gene Symbol	DHFR
Entrez Gene	1719
Alt Symbol	DHFRP1, DYR
Species	Human
Gene Type	protein-coding
Description	dihydrofolate reductase
Other Description	-
Swissprots	B4DDD2 P00374 Q6IRW8 Q14130
Accessions	AAA58484 CAA25409 EAW95859 EAW95860 P00374 AA489055 AK293146 BAG56693 AK297302 BAG59770 AK308492 AK312642 BAG35526 BC000192 AAH00192 BC003584 AAH03584 BC009634 BC070280 AAH70280 BC071996 AAH71996 CB988944 DQ892816 ABM83742 DQ896062 ABM87061 EU145592 ABX57718 J00140 AAA58485 V00507 CAA23765 NM_000791 NP_000782 NM_001290354 NP_001277283 NM_001290357 NP_001277286 NR_110936
Function	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFRL1. {ECO:0000269|PubMed:12096917, ECO:0000269|PubMed:21876188}.
Tissue Specificity	Widely expressed in fetal and adult tissues, including throughout the fetal and adult brains and whole blood. Expression is higher in the adult brain than in the fetal brain. {ECO:0000269|PubMed:21310276}.
Top Pathways	Folate biosynthesis, One carbon pool by folate

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-DHFR-cDNA-Clone - DC00082 from Abgent, a WuXi AppTec company Prices $252.45 Sizes 10 µg Species Human Accession BC000192

DHFR - MBS1272688 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC000192

Human DHFR cDNA clone(NM_000791.3) - CDFH005037 from Creative Biomart Species Human Accession NM_000791.3

Human DHFR ORF Clone(NM_000791.3) - CDCR337685 from Creative Biomart Species Human Accession NM_000791.3

Human DHFR ORF Clone(NM_000791.3) - CDCR337686 from Creative Biomart Species Human Accession NM_000791.3

Human DHFR ORF Clone(NM_000791.3) - CDCR337687 from Creative Biomart Species Human Accession NM_000791.3

Human DHFR ORF Clone(NM_000791.3) - CDCL160997 from Creative Biomart Species Human Accession NM_000791.3

Human DHFR ORF Clone(NM_000791.3) - CDCL160998 from Creative Biomart Species Human Accession NM_000791.3

Human Dihydrofolate reductase (DHFR) Gene ORF cDNA clone in cloning vector - HG14365-G from Sino Biological Species Human

Human Dihydrofolate reductase (DHFR) Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14365-CF from Sino Biological Species Human

Human Dihydrofolate reductase (DHFR) Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14365-NM from Sino Biological Species Human

Human Dihydrofolate reductase (DHFR) Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14365-CM from Sino Biological Species Human

Human Dihydrofolate reductase (DHFR) Gene ORF cDNA clone expression plasmid, N-His tag - HG14365-NH from Sino Biological Species Human

Human Dihydrofolate reductase (DHFR) Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14365-ANG from Sino Biological Species Human

Human Dihydrofolate reductase (DHFR) Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14365-ACR from Sino Biological Species Human

Human Dihydrofolate reductase (DHFR) Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14365-ACG from Sino Biological Species Human

Human Dihydrofolate reductase (DHFR) Gene ORF cDNA clone expression plasmid, N-HA tag - HG14365-NY from Sino Biological Species Human

Human Dihydrofolate reductase (DHFR) Gene ORF cDNA clone expression plasmid, C-His tag - HG14365-CH from Sino Biological Species Human

Human Dihydrofolate reductase (DHFR) Gene ORF cDNA clone expression plasmid - HG14365-UT from Sino Biological Species Human

Human Dihydrofolate reductase (DHFR) Gene ORF cDNA clone expression plasmid, C-HA tag - HG14365-CY from Sino Biological Species Human

Human Dihydrofolate reductase (DHFR) Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14365-NF from Sino Biological Species Human

Human DHFR ORF Clone(NM_000791.3) - CDCR337685 from Creative biogene Species Human

Human DHFR ORF Clone (BC000192) - CDCS405905 from Creative biogene Species Human Accession B0YJ76

Human DHFR ORF clone (BC000192) - CDCB159138 from Creative biogene Species Human

Human DHFR cDNA Clone(NM_000791.3) - CDFH005037 from Creative biogene Species Human

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