DHFR

Gene Symbol	DHFR
Entrez Gene	1719
Alt Symbol	DHFRP1, DYR
Species	Human
Gene Type	protein-coding
Description	dihydrofolate reductase
Other Description	-
Swissprots	B4DDD2 P00374 Q6IRW8 Q14130
Accessions	AAA58484 CAA25409 EAW95859 EAW95860 P00374 AA489055 AK293146 BAG56693 AK297302 BAG59770 AK308492 AK312642 BAG35526 BC000192 AAH00192 BC003584 AAH03584 BC009634 BC070280 AAH70280 BC071996 AAH71996 CB988944 DQ892816 ABM83742 DQ896062 ABM87061 EU145592 ABX57718 J00140 AAA58485 V00507 CAA23765 NM_000791 NP_000782 NM_001290354 NP_001277283 NM_001290357 NP_001277286 NR_110936
Function	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFRL1. {ECO:0000269|PubMed:12096917, ECO:0000269|PubMed:21876188}.
Tissue Specificity	Widely expressed in fetal and adult tissues, including throughout the fetal and adult brains and whole blood. Expression is higher in the adult brain than in the fetal brain. {ECO:0000269|PubMed:21310276}.
Top Pathways	Folate biosynthesis, One carbon pool by folate

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Dihydrofolate reductase (DHFR) full length protein - ab167972 from Abcam Category Protein Prices $352.00 Sizes 100 µg Source E. coli Species Human

Active human Dihydrofolate reductase (DHFR) full length protein - ab87755 from Abcam Category Protein Prices $239.00, $588.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Active mouse Dihydrofolate reductase (DHFR) full length protein - ab168723 from Abcam Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Mouse

Dihydrofolate reductase (DHFR) peptide - ab94547 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human Dihydrofolate reductase (DHFR) full length protein - ab104018 from Abcam Category Protein Source E. coli Species Human

DHFR Antibody Blocking Peptide - LS-E8905 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Dihydrofolate Reductase/DHFR Protein - NBP1-30207 from Novus Biologicals Category Protein Prices $229.00 Sizes 100 µg Source E.coli Species Human

Dihydrofolate Reductase/DHFR Recombinant Protein - H00001719-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Dihydrofolate Reductase/DHFR Partial Recombinant Protein - H00001719-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Dihydrofolate Reductase/DHFR Recombinant Protein - P3492 from Novus Biologicals Category Protein Prices $449.00 Sizes 100 µg Species Human

DHFR-Antibody-Center-Blocking-Peptide - BP7378c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DHFR-Antibody-C-term-Blocking-Peptide - BP7378a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DHFR Protein - GTX110710-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

DHFR Protein (OPPA02042) - OPPA02042 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 10 µg Source E. coli

Human DHFR protein - orb246326 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human Dihydrofolate Reductase protein - orb90071 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 10 μg, 50 μg Source E.coli

Mouse DHFR protein - orb168227 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 5 μg, 20 μg Source E. coli Species Mouse

DHFR protein (His tag) - 80R-1187 from Fitzgerald Category Protein Prices $180.00 Sizes 100 µg Source E.coli

DHFR / DHFRP1 (1-187, His-tag) - AR09254PU-L from Acris Antibodies Category Protein Prices $585.00 Sizes 500 µg Source E. coli Species Human

DHFR / DHFRP1 (1-187, His-tag) - AR09254PU-N from Acris Antibodies Category Protein Prices $270.00 Sizes 100 µg Source E. coli Species Human

DHFR / DHFRP1 - H00001719-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DHFR / DHFRP1 - H00001719-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DHFR / DHFRP1 - H00001719-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DHFR / DHFRP1 - H00001719-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DHFR / DHFRP1 - P3492 from Acris Antibodies Category Protein Prices $430.00 Sizes 100 µg Species Human

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