Gene Symbol |
FETUB
|
Entrez Gene |
26998
|
Alt Symbol |
16G2, Gugu, IRL685
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
fetuin B
|
Other Description |
fetuin-B|fetuin-like protein IRL685
|
Swissprots |
Q5J876 Q6DK58 E9PG06 Q1RMZ0 Q9Y6Z0 Q9UGM5 B2RCW6 Q6GRB6
|
Accessions |
CAC24999 EAW78185 EAW78186 Q9UGM5 AB017551 BAA78341 AF534529 AAQ10515 AJ242928 CAB62538 AK303859 BAH14069 AK309647 AK315309 BAG37713 AY373820 AAR22507 AY373821 AAR22508 BC069670 AAH69670 BC069820 AAH69820 BC074734 AAH74734 BC114616 AAI14617 BX115543 XM_005247350 XP_005247407 XM_005247351 XP_005247408 XM_011512681 XP_011510983 XM_011512682 XP_011510984 XM_011512683 XP_011510985 XM_011512684 XP_011510986 NM_001308077 NP_001295006 NM_001308079 NP_001295008 NM_014375 NP_055190
|
Function |
Protease inhibitor required for egg fertilization. Required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity). {ECO:0000250}.
|
Subcellular Location |
Secreted {ECO:0000250}.
|
Tissue Specificity |
Liver and testis.
|