Gene Symbol | FETUB |
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Entrez Gene | 26998 |
Alt Symbol | 16G2, Gugu, IRL685 |
Species | Human |
Gene Type | protein-coding |
Description | fetuin B |
Other Description | fetuin-B|fetuin-like protein IRL685 |
Swissprots | Q5J876 Q6DK58 E9PG06 Q1RMZ0 Q9Y6Z0 Q9UGM5 B2RCW6 Q6GRB6 |
Accessions | CAC24999 EAW78185 EAW78186 Q9UGM5 AB017551 BAA78341 AF534529 AAQ10515 AJ242928 CAB62538 AK303859 BAH14069 AK309647 AK315309 BAG37713 AY373820 AAR22507 AY373821 AAR22508 BC069670 AAH69670 BC069820 AAH69820 BC074734 AAH74734 BC114616 AAI14617 BX115543 XM_005247350 XP_005247407 XM_005247351 XP_005247408 XM_011512681 XP_011510983 XM_011512682 XP_011510984 XM_011512683 XP_011510985 XM_011512684 XP_011510986 NM_001308077 NP_001295006 NM_001308079 NP_001295008 NM_014375 NP_055190 |
Function | Protease inhibitor required for egg fertilization. Required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Liver and testis. |
fetuin-B CRISPR/Cas9 KO Plasmid (h) - sc-405331 from Santa Cruz Biotechnology
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fetuin-B HDR Plasmid (h) - sc-405331-HDR from Santa Cruz Biotechnology
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fetuin-B Double Nickase Plasmid (h) - sc-405331-NIC from Santa Cruz Biotechnology
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fetuin-B Double Nickase Plasmid (h2) - sc-405331-NIC-2 from Santa Cruz Biotechnology
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fetuin-B CRISPR Activation Plasmid (h) - sc-405331-ACT from Santa Cruz Biotechnology
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fetuin-B CRISPR Activation Plasmid (h2) - sc-405331-ACT-2 from Santa Cruz Biotechnology
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fetuin-B Lentiviral Activation Particles (h) - sc-405331-LAC from Santa Cruz Biotechnology
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fetuin-B Lentiviral Activation Particles (h2) - sc-405331-LAC-2 from Santa Cruz Biotechnology
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fetuin-B siRNA (h) - sc-45303 from Santa Cruz Biotechnology
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fetuin-B shRNA Plasmid (h) - sc-45303-SH from Santa Cruz Biotechnology
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fetuin-B shRNA (h) Lentiviral Particles - sc-45303-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU006411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8629 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8629 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03687 from Sigma-Aldrich
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FETUB siRNA (Human) - CRH8915 from Cohesion Biosciences
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FETUB - MBS8211586 from MyBioSource
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shRNA set against Human Fetub (NM_014375.2) - SHH294157 from Creative biogene
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shRNA set against Human FETUB(NM_014375.2) - SHH055865 from Creative biogene
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FETUB shRNA Plasmid (Human) - CHH8915 from Cohesion Biosciences
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FETUB miRNA 3'UTR clone - MiUTR1H-03613 from Creative biogene
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