GCNT2

Gene Symbol	GCNT2
Entrez Gene	2651
Alt Symbol	CCAT, CTRCT13, GCNT2C, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3, bA360O19.2, bA421M1.1
Species	Human
Gene Type	protein-coding
Description	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
Other Description	I beta-1,6-N-acetylglucosaminyltransferase|Ii blood group|N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase|beta-1,6-N-acetylglucosaminyltransferase 2
Swissprots	Q6T5E5 Q8N0V5 Q5T4J1 Q8NFS9 Q06430 Q5W0E9
Accessions	AAA99832 EAW55259 EAW55260 EAW55261 EAW55262 Q06430 Q8N0V5 Q8NFS9 AB078432 BAC66781 AB078433 BAC66782 AF401652 AAL50561 AF401653 AAL50562 AF458024 AAM73864 AF458025 AAM73865 AF458026 AAM73866 AF458027 AAM73867 AF458028 AAM74524 AF458029 AAM73869 AF458030 AAM73870 AK090483 BAC03464 AK098105 BAC05234 AK291195 BAF83884 AK291767 BAF84456 AK307329 AK307337 AK307373 AK310216 AK313426 BAG36218 AK313903 BAG36626 AL832714 AL832719 AY435145 AAR95646 AY435146 AAR95647 AY435147 AAR95648 BC074801 AAH74801 BC074802 AAH74802 BC130524 AAI30525 BX503586 BX647576 CAI46081 BX647668 DB208581 HQ258240 ADR82994 L19659 AAA81777 Z19550 CAA79610 XM_005248997 XP_005249054 XM_005248999 XP_005249056 XM_006715052 XP_006715115 XM_006715053 XP_006715116 XM_011514465 XP_011512767 XM_011514466 XP_011512768 XM_011514467 XP_011512769 XM_011514468 XP_011512770 XR_926136 XR_926137 XR_926138 NM_001491 NP_001482 NM_145649 NP_663624 NM_145655 NP_663630
Function	Branching enzyme that converts linear into branched poly-N-acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells. The expression of the blood group I antigen in erythrocytes is determined by isoform C.
Subcellular Location	Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity	In the adult, highly expressed in prostate and to a lesser extent in small intestine and colon. Barely detected in heart, brain, kidney and pancreas. No expression in placenta, lung, liver, skeletal muscle, spleen, thymus, testis, ovary and peripheral blood leukocytes. In fetus, highly expressed in brain and to a lesser extent in lung and kidney. Barely detected in liver. {ECO:0000269|PubMed:12424189, ECO:0000269|PubMed:9405606}.
Top Pathways	Glycosphingolipid biosynthesis - lacto and neolacto series

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GCNT2 full length protein - ab158506 from Abcam Category Protein Source Wheat germ Species Human

Human GCNT2 protein fragment - ab158507 from Abcam Category Protein Source Wheat germ Species Human

GCNT2 Antibody Blocking Peptide - LS-E114 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GCNT2 Antibody Blocking Peptide - LS-E5897 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GCNT2 Protein - H00002651-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human GCNT2 Protein - H00002651-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

GCNT2-Antibody-C-term-Blocking-peptide - BP10215b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GCNT2-Antibody-Center-Blocking-Peptide - BP18452c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GCNT2 / NACGT1 - H00002651-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

GCNT2 / NACGT1 - H00002651-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

GCNT2 / NACGT1 - H00002651-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

GCNT2 fusion protein - ag12370 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GCNT2 fusion protein - Ag12635 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human GCNT2, His-tagged - GCNT2-89H from Creative Biomart Category Protein Source HEK293 Species Human

Recombinant Aspartate Aminotransferase (AST) - RPB214Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Aspartate Aminotransferase (AST) - RPB214Hu51 from Cloud-clone Category Protein Source Yeast (Pichia pastor Species Human

Recombinant Human N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferas - CSB-YP854011HU CSB-EP854011HU CSB-BP854011HU CSB-MP854011HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferas - CSB-YP844048HU CSB-EP844048HU CSB-BP844048HU CSB-MP844048HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

GCNT2 Protein - abx163765 from Abbexa Category Protein Species Human

Glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) (GCNT2), transcript variant 3 (transcript variant 3) - TP315538 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

GCNT2 Protein - NBP1-88781PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

GCNT2-Blocking-Peptide-Center - BP22141c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GCNT2 Peptide, Human - M34GP06171H from Creative Peptides Category Peptide Source Synthetic. Species Human

N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A (GCNT2), Recombinant Protein - MBS1288522 from MyBioSource Category Protein Prices $1,175.00, $1,175.00, $1,395.00, $1,395.00, $1,885.00, $1,885.00, $2,350.00, $2,350.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform C (GCNT2), Recombinant Protein - MBS1309726 from MyBioSource Category Protein Prices $1,175.00, $1,175.00, $1,395.00, $1,395.00, $1,885.00, $1,885.00, $2,350.00, $2,350.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more