AUP1

Gene Symbol AUP1
Entrez Gene 550
Alt Symbol -
Species Human
Gene Type protein-coding
Description ancient ubiquitous protein 1
Other Description -
Swissprots Q9UNQ6 C0H5W8 Q9H866 Q9Y679 Q9Y685
Accessions EAW99622 EAW99623 EAW99624 EAW99625 Q9Y679 AF100746 AAD43010 AF100753 AAD43017 AF100754 AAD43018 AF165515 AAF86645 AI206563 AI580873 AK023983 BAB14753 AK055566 AK293121 BAF85810 AK301398 BAG62933 AK304886 BAG65623 AK308231 AK310159 BC001658 AAH01658 BC033646 AAH33646 CR749661 CAH18454 CR999537 CX164419 EU831790 ACE87308 EU831868 ACE86627 HY078082 XM_005264392 XP_005264449 NM_181575 NP_853553 NR_126510 NR_126511
Function May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. {ECO:0000269|PubMed:18711132}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:12042322, ECO:0000269|PubMed:18711132}; Single-pass type III membrane protein {ECO:0000269|PubMed:12042322, ECO:0000269|PubMed:18711132}; Cytoplasmic side {ECO:0000269|PubMed:12042322, ECO:0000269|PubMed:18711132}.
Tissue Specificity Detected in blood platelets and leukocytes (at protein level). Ubiquitous. Highly expressed in placenta, liver, kidney, skeletal muscle, heart and brain. {ECO:0000269|PubMed:12042322}.

SignalSilence ® AUP1 siRNA I - 14176 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from 293 cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® AUP1 siRNA I (+), or SignalSilence ® AUP1 siRNA II #14183 (+), using AUP1 Antibody #14035 (upper) or GAPDH (D16H11) XP ® Rabbit mAb #5174 (lower). The AUP1 Antibody confirms silencing of AUP1 expression, while the GAPDH (D16H11) XP ® Rabbit mAb is used as a loading control.

SignalSilence ® AUP1 siRNA II - 14183 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from 293 cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® AUP1 siRNA I #14176 (+), or SignalSilence ® AUP1 siRNA II (+), using AUP1 Antibody #14035 (upper) or GAPDH (D16H11) XP ® Rabbit mAb #5174 (lower). The AUP1 Antibody confirms silencing of AUP1 expression, while the GAPDH (D16H11) XP ® Rabbit mAb is used as a loading control.

AUP1 CRISPR/Cas9 KO Plasmid (h) - sc-410699 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AUP1 HDR Plasmid (h) - sc-410699-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AUP1 Double Nickase Plasmid (h) - sc-410699-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AUP1 Double Nickase Plasmid (h2) - sc-410699-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AUP1 CRISPR Activation Plasmid (h) - sc-410699-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AUP1 CRISPR Activation Plasmid (h2) - sc-410699-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AUP1 Lentiviral Activation Particles (h) - sc-410699-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AUP1 Lentiviral Activation Particles (h2) - sc-410699-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AUP1 siRNA (h) - sc-94537 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AUP1 shRNA Plasmid (h) - sc-94537-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AUP1 shRNA (h) Lentiviral Particles - sc-94537-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU133841 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3771 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3771 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AUP1 siRNA (Human) - CRH0379 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AUP1 - MBS8218186 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AUP1 (NM_181575.3) - SHH243710 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human AUP1(NM_181575.3) - SHG086281 from Creative biogene

Category siRNA
Species Reactivities Human

Human AUP1 siRNA - orb260881 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AUP1 shRNA Plasmid (Human) - CHH0379 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AUP1 miRNA 3'UTR clone - MiUTR1H-00745 from Creative biogene

Species Reactivities Human
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