| Gene Symbol |
TAS2R14
|
| Entrez Gene |
50840
|
| Alt Symbol |
T2R14, TRB1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
taste receptor, type 2, member 14
|
| Other Description |
taste receptor family B member 1|taste receptor type 2 member 14|taste receptor, family B, member 1
|
| Swissprots |
Q645X3 Q9NYV8
|
| Accessions |
AAF43911 BAD98002 BAD98003 BAD98004 CAI53561 EAW96222 Q9NYV8 AK123548 BAC85643 BC069148 AAH69148 BC101993 AAI01994 BC101994 AAI01995 BC103699 AAI03700 NM_023922 NP_076411
|
| Function |
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells.
|
| Top Pathways |
Taste transduction
|