NUP85

Gene Symbol	NUP85
Entrez Gene	79902
Alt Symbol	FROUNT, Nup75
Species	Human
Gene Type	protein-coding
Description	nucleoporin 85kDa
Other Description	nuclear pore complex protein Nup85|nucleoporin Nup75|nucleoporin Nup85
Swissprots	Q9H9U1 B4DPW1 B4DMQ3 Q8NDI4 Q9BW27
Accessions	EAW89251 Q9BW27 AF498261 AAM18528 AF514995 AAM76706 AK022611 BAB14130 AK124501 BAG54043 AK295694 BAH12158 AK297574 BAG59965 AK298519 BAG60723 AK302426 BAG63729 AL833893 CAD38749 BC000697 AAH00697 BM973048 DA375719 DA787201 DC424627 XM_005257690 XP_005257747 XM_005257692 XP_005257749 XM_005257693 XP_005257750 XM_006722094 XP_006722157 XM_011525267 XP_011523569 XM_011525268 XP_011523570 XR_243683 XR_429921 XR_934552 NM_001303276 NP_001290205 NM_024844 NP_079120
Function	Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2- activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl- inositol 3-kinase-Rac-lammellipodium protrusion cascade. {ECO:0000269|PubMed:12718872, ECO:0000269|PubMed:15995708, ECO:0000269|PubMed:16807356}.
Subcellular Location	Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Nucleus membrane. Note=During mitosis, localizes to the kinetochores and spindle poles. Upon CCl2 stimulation translocates from the cytoplasm to the membrane and colocalizes with CCR2 at the front of migrating cells.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Pericentrin 1 full length protein - ab132205 from Abcam Category Protein Source Wheat germ Species Human

Human Pericentrin 1 peptide - ab45561 from Abcam Category Peptide Species Human

NUP85 / Pericentrin 1 Antibody Blocking Peptide - LS-E25650 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Nucleoporin NUP85/Pericentrin 1 Protein - H00079902-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Pericentrin 1/NUP85 blocking peptide - GTX19044-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat

Pericentrin 1 Peptide - AC21-0481-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NUP85 / NUP75 / PCNT1 - H00079902-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NUP85 / NUP75 / PCNT1 - H00079902-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NUP85 Peptide - 45-102P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

Pericentrin fusion protein - ag7086 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Pericentrin fusion protein - ag7158 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Nucleoporin 85kDa (NUP85) - RPB110Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Nucleoporin 85kDa (NUP85) - RPB110Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Nucleoporin 85kDa (NUP85) - RPB110Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Nuclear pore complex protein Nup85(NUP85) - CSB-YP874821HU CSB-EP874821HU CSB-BP874821HU CSB-MP874821HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Nucleoporin 85kDa Protein (Recombinant) - abx168228 from Abbexa Category Protein Source Human Species Human

Pericentrin 1/NUP85, Peptide - MBS425477 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat

Nucleoporin NUP85/Pericentrin 1 Recombinant Protein Antigen - NBP2-31860PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NUP85-Blocking-Peptide-N-Term - BP22048a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NUP85 Peptide, Human - M34GP10747H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Nucleoporin 85kDa (NUP85) - RPU53019 from Biomatik Category Protein Prices $194.00, $396.00, $605.00, $721.60 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

NUP85 Recombinant Protein (OPCD05862) - OPCD05862 from Aviva Systems Biology Category Protein Source E.coli Species Human

Nucleoporin NUP85/Pericentrin 1 Recombinant Protein Antigen - NBP2-56709PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Nuclear pore complex protein Nup85 (NUP85), Recombinant Protein - MBS1473301 from MyBioSource Category Protein Prices $1,455.00, $1,455.00, $1,685.00, $1,685.00, $2,475.00, $2,475.00, $2,920.00, $2,920.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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