Gene Symbol | APOC2 |
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Entrez Gene | 344 |
Alt Symbol | APO-CII, APOC-II |
Species | Human |
Gene Type | protein-coding |
Description | apolipoprotein C-II |
Other Description | apolipoprotein C2 |
Swissprots | Q9UDE3 Q9BS39 P02655 C0JYY4 Q9UNK3 |
Accessions | AAA98743 AAB59380 AAQ91814 ACN81313 CAA28798 EAW57311 EAW57312 EAW57313 P02655 AA883870 AF113884 AAD28193 AV694494 BC005348 AAH05348 BC065270 AAH65270 BT006708 AAP35354 BU596546 EU832654 ACE87745 EU832732 ACE87064 M29844 AAA51743 X00568 CAA25234 NM_000483 NP_000474 |
Function | Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL. {ECO:0000269|PubMed:2209608, ECO:0000303|PubMed:22304839}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:3525527}. |
Tissue Specificity | Liver and intestine. {ECO:0000269|PubMed:6546757}. |
Human-APOC2-cDNA-Clone - DC01738 from Abgent, a WuXi AppTec company
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APOC2 - MBS1275456 from MyBioSource
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APOC2 - MBS1275743 from MyBioSource
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Human APOC2 ORF Clone(NM_000483.4) - CDCL154132 from Creative Biomart
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Human APOC2 ORF Clone(NM_000483.4) - CDCL154133 from Creative Biomart
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Human APOC2 ORF Clone(NM_000483.4) - CDCL154134 from Creative Biomart
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Human APOC2/Apolipoprotein CII Gene ORF cDNA clone expression plasmid - HG12469-UT from Sino Biological
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Human APOC2 ORF Clone (BC005348) - CDCS405688 from Creative biogene
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Human APOC2 ORF Clone (BC065270) - CDCS405689 from Creative biogene
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