Gene Symbol | RPN1 |
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Entrez Gene | 6184 |
Alt Symbol | OST1, RBPH1 |
Species | Human |
Gene Type | protein-coding |
Description | ribophorin I |
Other Description | RPN-I|dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit|dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1|dolichyl-diphosphooligosaccharide-protein glycosyltransferase 67 kDa subunit|oligosaccharyltransferase 1 homolog|oligosaccharyltransferase complex subunit (non-catalytic)|ribophorin-1 |
Swissprots | P04843 Q68DT1 B2R5Z0 D3DNB6 |
Accessions | CAH05344 CAH05363 EAW79306 EAW79307 EAW79308 EAW79309 P04843 AK223595 BAD97315 AK296905 BAG59461 AK297513 BAH12600 AK297941 BAG60257 AK312369 BAG35287 BC007995 AAH07995 BC010839 AAH10839 BF930946 BG720812 CR456742 CAG33023 CR749284 CAH18139 JF432331 ADZ15548 Y00281 CAA68392 NM_002950 NP_002941 |
Function | Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. |
Subcellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Tissue Specificity | Expressed in all tissues tested. {ECO:0000269|PubMed:12887896}. |
Top Pathways | N-Glycan biosynthesis, Protein processing in endoplasmic reticulum |
Ribophorin I (C-15) - sc-12164 from Santa Cruz Biotechnology
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Ribophorin I (E-16) - sc-12163 from Santa Cruz Biotechnology
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Ribophorin I (H-50) - sc-25559 from Santa Cruz Biotechnology
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Ribophorin I (E-7) - sc-48367 from Santa Cruz Biotechnology
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Anti-Ribophorin I antibody - ab197819 from Abcam
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Anti-Ribophorin I antibody - ab86267 from Abcam
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Anti-Ribophorin I antibody - ab74725 from Abcam
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Anti-Ribophorin I antibody - ab38451 from Abcam
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Anti-Ribophorin I antibody - ab58336 from Abcam
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Anti-Ribophorin I antibody [3E1] - ab123904 from Abcam
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Anti-Ribophorin I antibody [EPR17044(B)] - ab197888 from Abcam
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Anti-Ribophorin I antibody - C-terminal - ab137668 from Abcam
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Anti-RPN1 / Ribophorin I Antibody (clone 5B1) - LS-C173362 from LifeSpan Bioscience
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Anti-RPN1 / Ribophorin I Antibody (clone 6F2) - LS-C173354 from LifeSpan Bioscience
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Anti-RPN1 / Ribophorin I Antibody (clone 2C10-2F6) - LS-C198117 from LifeSpan Bioscience
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Anti-RPN1 / Ribophorin I Antibody (aa559-587, APC) - LS-C268512 from LifeSpan Bioscience
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Anti-RPN1 / Ribophorin I Antibody (aa559-587, AP) - LS-C268513 from LifeSpan Bioscience
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Anti-RPN1 / Ribophorin I Antibody (clone 2G9) - LS-C173360 from LifeSpan Bioscience
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Anti-RPN1 / Ribophorin I Antibody (aa559-587, Biotin) - LS-C268514 from LifeSpan Bioscience
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Anti-RPN1 / Ribophorin I Antibody (aa559-587, FITC) - LS-C268515 from LifeSpan Bioscience
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Anti-RPN1 / Ribophorin I Antibody (aa559-587, Azide-free, HRP) - LS-C268516 from LifeSpan Bioscience
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Anti-RPN1 / Ribophorin I Antibody (aa559-587, PE) - LS-C268518 from LifeSpan Bioscience
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Anti-RPN1 / Ribophorin I Antibody (C-Terminus, APC) - LS-C282219 from LifeSpan Bioscience
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Anti-RPN1 / Ribophorin I Antibody (C-Terminus, Biotin) - LS-C282220 from LifeSpan Bioscience
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Anti-RPN1 / Ribophorin I Antibody (C-Terminus, FITC) - LS-C282221 from LifeSpan Bioscience
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