Gene Symbol | RPN1 |
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Entrez Gene | 6184 |
Alt Symbol | OST1, RBPH1 |
Species | Human |
Gene Type | protein-coding |
Description | ribophorin I |
Other Description | RPN-I|dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit|dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1|dolichyl-diphosphooligosaccharide-protein glycosyltransferase 67 kDa subunit|oligosaccharyltransferase 1 homolog|oligosaccharyltransferase complex subunit (non-catalytic)|ribophorin-1 |
Swissprots | P04843 Q68DT1 B2R5Z0 D3DNB6 |
Accessions | CAH05344 CAH05363 EAW79306 EAW79307 EAW79308 EAW79309 P04843 AK223595 BAD97315 AK296905 BAG59461 AK297513 BAH12600 AK297941 BAG60257 AK312369 BAG35287 BC007995 AAH07995 BC010839 AAH10839 BF930946 BG720812 CR456742 CAG33023 CR749284 CAH18139 JF432331 ADZ15548 Y00281 CAA68392 NM_002950 NP_002941 |
Function | Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. |
Subcellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Tissue Specificity | Expressed in all tissues tested. {ECO:0000269|PubMed:12887896}. |
Top Pathways | N-Glycan biosynthesis, Protein processing in endoplasmic reticulum |
Human Ribophorin I full length protein - ab152663 from Abcam
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Human Ribophorin I full length protein - ab152664 from Abcam
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RPN1 / Ribophorin I Antibody Blocking Peptide - LS-E4636 from LifeSpan Bioscience
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RPN1 / Ribophorin I Antibody Blocking Peptide - LS-E14748 from LifeSpan Bioscience
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RPN1 / Ribophorin I Antibody Blocking Peptide - LS-E14749 from LifeSpan Bioscience
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RPN1 / Ribophorin I Antibody Blocking Peptide - LS-E6953 from LifeSpan Bioscience
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Recombinant Human Ribophorin I Protein - H00006184-P02 from Novus Biologicals
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Recombinant Human Ribophorin I Protein - H00006184-P01 from Novus Biologicals
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Ribophorin I Peptide - P1087 from Novus Biologicals
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Recombinant Human Ribophorin I Protein - H00006184-G01-10ug from Novus Biologicals
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RPN1-Antibody-C-term-Blocking-Peptide - BP16998b from Abgent, a WuXi AppTec company
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Ribophorin-RPN1-Antibody-C-term-Blocking-peptide - BP2409b from Abgent, a WuXi AppTec company
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Human DDOST protein - orb245228 from Biorbyt
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Ribophorin I Blocking Peptide - 33R-9295 from Fitzgerald
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Ribophorin I Blocking Peptide - 33R-1015 from Fitzgerald
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Human Ribophorin I Protein - abx068930 from Abbexa
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Human Ribophorin I Protein - abx068932 from Abbexa
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Human Ribophorin I Protein - abx068931 from Abbexa
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Ribophorin-1 / RPN1 - H00006184-P01-10 from Acris Antibodies
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Ribophorin-1 / RPN1 - H00006184-P01-25 from Acris Antibodies
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Ribophorin-1 / RPN1 - H00006184-P02 from Acris Antibodies
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Ribophorin-1 / RPN1 - H00006184-P02-10 from Acris Antibodies
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Ribophorin-1 / RPN1 - H00006184-P02-25 from Acris Antibodies
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Ribophorin I (RPN1), Human - 20-8576 from ARP American Research Products
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Ribophorin I (RPN1), Human - 20-8577 from ARP American Research Products
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