| Gene Symbol |
METTL11B
|
| Entrez Gene |
149281
|
| Alt Symbol |
C1orf184, HOMT1B, NTM1B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
methyltransferase like 11B
|
| Other Description |
X-Pro-Lys N-terminal protein methyltransferase 1B|alpha N-terminal protein methyltransferase 1B|methyltransferase-like protein 11B
|
| Swissprots |
Q5VVY1 B2RXI0
|
| Accessions |
Q5VVY1 BC157860 AAI57861 BC171858 AAI71858 XM_011509232 XP_011507534 XM_011509233 XP_011507535 XM_011509234 XP_011507536 NM_001136107 NP_001129579
|
| Function |
Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]- Pro-Lys when the initiator Met is cleaved. Specifically catalyzes monomethylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and Pro in the Pro-Pro-Lys motif. May activate NTMT1 by priming its substrates for trimethylation. {ECO:0000269|PubMed:24090352}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:24090352}.
|