| Gene Symbol | MAP2K2 |
|---|---|
| Entrez Gene | 5605 |
| Alt Symbol | CFC4, MAPKK2, MEK2, MKK2, PRKMK2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | mitogen-activated protein kinase kinase 2 |
| Other Description | ERK activator kinase 2|MAP kinase kinase 2|MAPK/ERK kinase 2|dual specificity mitogen-activated protein kinase kinase 2|mitogen-activated protein kinase kinase 2, p45 |
| Swissprots | P36507 |
| Accessions | EAW69262 EAW69263 EAW69264 EAW69265 P36507 AA312322 AK093125 BAG52659 AK126446 AK129586 BAC85187 BC000471 AAH00471 BC018645 AAH18645 BX538081 CAD98005 DQ893601 ABM84527 DQ895060 ABM85986 L11285 XM_006722799 XP_006722862 XM_011528133 XP_011526435 NM_030662 NP_109587 |
| Function | Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). {ECO:0000250}. |
| Top Pathways | Rap1 signaling pathway, Choline metabolism in cancer, cGMP-PKG signaling pathway, Prolactin signaling pathway, Sphingolipid signaling pathway |