Gene Symbol | MAP2K2 |
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Entrez Gene | 5605 |
Alt Symbol | CFC4, MAPKK2, MEK2, MKK2, PRKMK2 |
Species | Human |
Gene Type | protein-coding |
Description | mitogen-activated protein kinase kinase 2 |
Other Description | ERK activator kinase 2|MAP kinase kinase 2|MAPK/ERK kinase 2|dual specificity mitogen-activated protein kinase kinase 2|mitogen-activated protein kinase kinase 2, p45 |
Swissprots | P36507 |
Accessions | EAW69262 EAW69263 EAW69264 EAW69265 P36507 AA312322 AK093125 BAG52659 AK126446 AK129586 BAC85187 BC000471 AAH00471 BC018645 AAH18645 BX538081 CAD98005 DQ893601 ABM84527 DQ895060 ABM85986 L11285 XM_006722799 XP_006722862 XM_011528133 XP_011526435 NM_030662 NP_109587 |
Function | Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). {ECO:0000250}. |
Top Pathways | Rap1 signaling pathway, Choline metabolism in cancer, cGMP-PKG signaling pathway, Prolactin signaling pathway, Sphingolipid signaling pathway |
SignalSilence ® MEK2 siRNA II - 6532 from Cell Signaling Technology
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SignalSilence ® MEK2 siRNA I - 6431 from Cell Signaling Technology
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MEK-2 CRISPR/Cas9 KO Plasmid (h) - sc-402732 from Santa Cruz Biotechnology
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MEK-2 HDR Plasmid (h) - sc-402732-HDR from Santa Cruz Biotechnology
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MEK-2 Double Nickase Plasmid (h) - sc-402732-NIC from Santa Cruz Biotechnology
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MEK-2 Double Nickase Plasmid (h2) - sc-402732-NIC-2 from Santa Cruz Biotechnology
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MEK-2 CRISPR Activation Plasmid (h) - sc-402732-ACT from Santa Cruz Biotechnology
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MEK-2 CRISPR Activation Plasmid (h2) - sc-402732-ACT-2 from Santa Cruz Biotechnology
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MEK-2 Lentiviral Activation Particles (h) - sc-402732-LAC from Santa Cruz Biotechnology
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MEK-2 Lentiviral Activation Particles (h2) - sc-402732-LAC-2 from Santa Cruz Biotechnology
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MEK-2 siRNA (h) - sc-35905 from Santa Cruz Biotechnology
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MEK-2 shRNA Plasmid (h) - sc-35905-SH from Santa Cruz Biotechnology
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MEK-2 shRNA (h) Lentiviral Particles - sc-35905-V from Santa Cruz Biotechnology
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MEK2 RNAi - H00005605-R02 from Novus Biologicals
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MISSION® siRNA - SIHK1099 from Sigma-Aldrich
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MISSION® siRNA - SIHK1100 from Sigma-Aldrich
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MISSION® siRNA - SIHK1101 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1591 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1591 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02314 from Sigma-Aldrich
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MAP2K2 siRNA (Human) - CRH3775 from Cohesion Biosciences
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shRNA set against Human MAP2K2 (NM_030662.3) - SHH337539 from Creative biogene
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MAP2K2 shRNA Plasmid (Human) - CHH3775 from Cohesion Biosciences
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MAP2K2 miRNA 3'UTR clone - MiUTR3H-04005 from Creative biogene
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