MAP2K2

Gene Symbol MAP2K2
Entrez Gene 5605
Alt Symbol CFC4, MAPKK2, MEK2, MKK2, PRKMK2
Species Human
Gene Type protein-coding
Description mitogen-activated protein kinase kinase 2
Other Description ERK activator kinase 2|MAP kinase kinase 2|MAPK/ERK kinase 2|dual specificity mitogen-activated protein kinase kinase 2|mitogen-activated protein kinase kinase 2, p45
Swissprots P36507
Accessions EAW69262 EAW69263 EAW69264 EAW69265 P36507 AA312322 AK093125 BAG52659 AK126446 AK129586 BAC85187 BC000471 AAH00471 BC018645 AAH18645 BX538081 CAD98005 DQ893601 ABM84527 DQ895060 ABM85986 L11285 XM_006722799 XP_006722862 XM_011528133 XP_011526435 NM_030662 NP_109587
Function Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). {ECO:0000250}.
Top Pathways Rap1 signaling pathway, Choline metabolism in cancer, cGMP-PKG signaling pathway, Prolactin signaling pathway, Sphingolipid signaling pathway

MEK2 (13E3) Rabbit mAb - 9147 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone 13E3
Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence ® Control siRNA (Fluorescein Conjugate) #6201 (-) or SignalSilence ® MEK2 siRNA II (+), using MEK2 (13E3) Rabbit mAb #9147 and α-Tubulin (11H10) Rabbit mAb #2125. MEK2 (13E3) Rabbit mAb confirms silencing of MEK2 expression, while the α-Tubulin (11H10) Rabbit mAb is used to control for loading and specificity of MEK2 siRNA.

MEK2 Antibody - 9125 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa, NIH/3T3, C6 and COS cells, using MEK2 Antibody.

MEK-2 (A-1) - sc-13159 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MEK-2 (A-1): sc-13159. Western blot analysis of MEK-2 expression in non-transfected 293T: sc-117752 (A), mouse MEK-2 transfected 293T: sc-121596 (B) and NIH/3T3 (C) whole cell lysates.

MEK-2 (N-20) - sc-524 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MEK-2 (N-20): sc-524. Western blot analysis of MEK-2 expression in Jurkat (A), K-562 (B), NIH/3T3 (C) and WEHI-231 (D) whole cell lysates.

MEK-2 (C-16) - sc-525 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MEK-2 (C-16): sc-525. Western blot analysis of MEK-2 expression in non-transfected 293T: sc-117752 (A), mouse MEK-2 transfected 293T: sc-121596 (B) and NIH/3T3 (C) whole cell lysates.

MEK-2 (8E8) - sc-81473 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
MEK-2 (8E8): sc-81473. Western blot analysis of MEK-2 expression in NIH/3T3 whole cell lysate.

MEK-2 (96) - sc-136261 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
MEK-2 (96): sc-136261. Immunofluorescence staining of human fibroblast cells showing cytoplasmic localization.

p-MEK-2 (Thr 394) - sc-101734 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of phosphorylated MEK-2 expression in cancerous ovary tissue cell extract (A,B,C). Blots were probed with p-MEK-2 (Thr 394): sc-101734 preincubated with its cognate phosphorylated peptide (A,B) and p-MEK-2 (Thr 394): sc-101734 (C).

Anti-MEK2 (phospho T394) antibody - ab30622 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MEK2 (phospho T394) antibody (ab30622) at 1/500 dilutionLane 1 : extracts from ovary cancer cells.Lane 2 : extracts from ovary cancer cells, preincubated with synthesized non phosphopeptideLane 3 : extracts from ovary cancer cells, preincubated with synthesized phosphopeptide (negative control).

Anti-MEK2 (phospho T394) antibody - ab131095 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MEK2 (phospho T394) antibody (ab131095) at 1/500 dilutionLane 1 : HepG2 cell extract, untreatedLane 2 : HepG2 cell extract, treated with UVLane 3 : HeLa cell extract, untreatedLane 4 : HeLa cell extract, treated with UV

Anti-MEK2 (phospho T394) antibody - ab192220 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MEK2 (phospho T394) antibody (ab192220) at 1/500 dilutionLane 1 : ovary cancer whole cell lysate with antigen-specific peptideLane 2 : ovary cancer whole cell lysateLysates/proteins at 12.5 µg per lane.

Anti-MEK2 (phospho T394) antibody - ab118642 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab118642, at 10 µg/ml, staining MEK2 (phospho T394) in formalin fixed, paraffin embedded Human skin tissue by Immunohistochemistry. Detection utilized biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-MEK2 antibody - ab28834 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Ab28834 staining MEK2 in paraffin embedded human breast carcinoma tissue by Immunohistochemistry. Left image: untreated. Right image: preincubated with synthesized peptide.

Anti-MEK2 antibody - ab71828 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-MEK2 antibody (ab71828) at 1/100 dilution + mouse liver tissue lysate at 12.5 µg

Anti-MEK2 antibody - ab126801 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MEK2 antibody (ab126801) at 1/1000 dilutionLane 1 : Tagged human recombinant MEK1Lane 2 : Tagged human recombinant MEK2Lysates/proteins at 0.02 µg per lane.

Anti-MEK2 antibody - ab185934 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
All lanes : Anti-MEK2 antibody (ab185934) at 0.3 µg/mlLane 1 : Daudi cell lysateLane 2 : Jurkat cell lysateLane 3 : K562 cell lysateLane 4 : Molt4 cell lysateLysates/proteins at 35 µg per lane.

Anti-MEK2 antibody [1A1] - ab70590 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A1
All lanes : Anti-MEK2 antibody [1A1] (ab70590) at 1/2000 dilutionLane 1 : MCF-7 cell lysateLane 2 : U937 cell lysateLane 3 : Jurkat T cell lysateLane 4 : K562 cell lysate

Anti-MEK2 antibody [7F5] - ab93924 from Abcam

Host Mouse
Clonality Monoclonal
Clone 7F5
All lanes : Anti-MEK2 antibody [7F5] (ab93924) at 1/1000 dilutionLane 1 : PC-12 cell lysateLane 2 : Jurkat cell lysateLane 3 : HeLa cell lysateLane 4 : NIH/3T3 cell lysate

Anti-MEK2 antibody [Y78] - ab32517 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y78
Anti-MEK2 antibody [Y78] (ab32517) at 1/10000 dilution + Jurkat cell lysate

Anti-MEK2 antibody [Y78] (Alexa Fluor® 488) - ab200606 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y78
ab200606 staining MEK2 in HeLa cells. The cells were fixed with 100% methanol (5min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab200606 at 1/100 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at 2µg/ml (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-MEK2 antibody [Y78] (Alexa Fluor® 647) - ab200519 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y78
ab200519 staining MEK2 in HeLa cells. The cells were fixed with 4% formaldehyde (10min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab200519 at 1/200 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at 2µg/ml (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-MAP2K2 / MKK2 / MEK2 Antibody (aa35-63, APC) - LS-C223165 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAP2K2 / MKK2 / MEK2 Antibody (aa35-63, FITC) - LS-C223166 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAP2K2 / MKK2 / MEK2 Antibody (aa35-63, Biotin) - LS-C223167 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAP2K2 / MKK2 / MEK2 Antibody (aa35-63, PE) - LS-C223169 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more