| Gene Symbol |
LRP3
|
| Entrez Gene |
4037
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
low density lipoprotein receptor-related protein 3
|
| Other Description |
105 kDa low-density lipoprotein receptor-related protein|CTD-2540B15.13|LRP-3|hLRp105|low-density lipoprotein receptor-related protein 3
|
| Swissprots |
B4DKF2 B3KQD6 O75074
|
| Accessions |
O75074 AB009462 BAA32330 AF085860 AK074751 BAG51998 AK126750 AK129963 BAC85262 AK295505 BAG58424 AK296536 BAG59164 AK316314 BAH14685 BC007408 AAH07408 BU739456 DA496540 DR002806 EU176387 ABW03838 HG510641 XM_005258945 XP_005259002 NM_002333 NP_002324
|
| Function |
Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Membrane, coated pit {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte. {ECO:0000269|PubMed:9693042}.
|