Gene Symbol | LRP3 |
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Entrez Gene | 4037 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | low density lipoprotein receptor-related protein 3 |
Other Description | 105 kDa low-density lipoprotein receptor-related protein|CTD-2540B15.13|LRP-3|hLRp105|low-density lipoprotein receptor-related protein 3 |
Swissprots | B4DKF2 B3KQD6 O75074 |
Accessions | O75074 AB009462 BAA32330 AF085860 AK074751 BAG51998 AK126750 AK129963 BAC85262 AK295505 BAG58424 AK296536 BAG59164 AK316314 BAH14685 BC007408 AAH07408 BU739456 DA496540 DR002806 EU176387 ABW03838 HG510641 XM_005258945 XP_005259002 NM_002333 NP_002324 |
Function | Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Membrane, coated pit {ECO:0000250}. |
Tissue Specificity | Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte. {ECO:0000269|PubMed:9693042}. |
LRP3 CRISPR/Cas9 KO Plasmid (h) - sc-408747 from Santa Cruz Biotechnology
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LRP3 HDR Plasmid (h) - sc-408747-HDR from Santa Cruz Biotechnology
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LRP3 Double Nickase Plasmid (h) - sc-408747-NIC from Santa Cruz Biotechnology
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LRP3 Double Nickase Plasmid (h2) - sc-408747-NIC-2 from Santa Cruz Biotechnology
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LRP3 CRISPR Activation Plasmid (h) - sc-408747-ACT from Santa Cruz Biotechnology
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LRP3 CRISPR Activation Plasmid (h2) - sc-408747-ACT-2 from Santa Cruz Biotechnology
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LRP3 Lentiviral Activation Particles (h) - sc-408747-LAC from Santa Cruz Biotechnology
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LRP3 Lentiviral Activation Particles (h2) - sc-408747-LAC-2 from Santa Cruz Biotechnology
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LRP3 siRNA (h) - sc-97441 from Santa Cruz Biotechnology
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LRP3 shRNA Plasmid (h) - sc-97441-SH from Santa Cruz Biotechnology
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LRP3 shRNA (h) Lentiviral Particles - sc-97441-V from Santa Cruz Biotechnology
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LRP3 RNAi - H00004037-R02 from Novus Biologicals
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MISSION® esiRNA - EHU138851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12694 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12694 from Sigma-Aldrich
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LRP3 siRNA (Human) - CRH2729 from Cohesion Biosciences
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shRNA set against Human LRP3 (NM_002333.3) - SHH334031 from Creative biogene
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Human LRP3 siRNA - orb263231 from Biorbyt
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LRP3 shRNA Plasmid (Human) - CHH2729 from Cohesion Biosciences
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LRP3 miRNA 3'UTR clone - MiUTR3H-05726 from Creative biogene
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