| Gene Symbol |
Polr1e
|
| Entrez Gene |
64424
|
| Alt Symbol |
53kDa, AU042259, D030019D19Rik, Paf53, Praf1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
polymerase (RNA) I polypeptide E
|
| Other Description |
DNA-directed RNA polymerase I subunit E|DNA-directed RNA polymerase I subunit RPA49|RNA polymerase I associated factor (Paf53)|RNA polymerase I subunit A49|RNA polymerase I-associated factor 53|polymerase (RNA) I associated factor 1
|
| Swissprots |
B1AXQ6 Q8BQG9 Q62034 B1AXQ7 Q8K202
|
| Accessions |
EDL02410 EDL02411 Q8K202 AK050780 BAC34409 AK083948 AK132556 BAE21232 BC034783 AAH34783 BY328290 D14336 BAA03266 NM_001285800 NP_001272729 NM_022811 NP_073722
|
| Function |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF. {ECO:0000269|PubMed:8641287, ECO:0000269|PubMed:9254723}.
|
| Subcellular Location |
Nucleus, nucleolus {ECO:0000269|PubMed:8641287, ECO:0000269|PubMed:9254723}.
|
| Top Pathways |
Purine metabolism, RNA polymerase, Pyrimidine metabolism
|