| Gene Symbol |
ETV3
|
| Entrez Gene |
2117
|
| Alt Symbol |
METS, PE-1, PE1, bA110J1.4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ets variant 3
|
| Other Description |
ETS domain transcriptional repressor PE1|ETS translocation variant 3|ets variant gene 3, ETS family transcriptional repressor|mitogenic Ets transcriptional suppressor
|
| Swissprots |
P41162 B4E3M7 Q9BX30 Q8TAC8
|
| Accessions |
EAW52888 EAW52889 P41162 AF218540 AAK56846 AK304789 BAG65539 AK316274 BAH14645 BC022868 AAH22868 DQ893155 ABM84081 DQ896758 ABM87757 L16464 AAA60949 XM_006711210 XP_006711273 NM_001145312 NP_001138784 NM_005240 NP_005231
|
| Function |
Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity. {ECO:0000269|PubMed:12007404}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00237}.
|