Gene Symbol | ETV3 |
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Entrez Gene | 2117 |
Alt Symbol | METS, PE-1, PE1, bA110J1.4 |
Species | Human |
Gene Type | protein-coding |
Description | ets variant 3 |
Other Description | ETS domain transcriptional repressor PE1|ETS translocation variant 3|ets variant gene 3, ETS family transcriptional repressor|mitogenic Ets transcriptional suppressor |
Swissprots | P41162 B4E3M7 Q9BX30 Q8TAC8 |
Accessions | EAW52888 EAW52889 P41162 AF218540 AAK56846 AK304789 BAG65539 AK316274 BAH14645 BC022868 AAH22868 DQ893155 ABM84081 DQ896758 ABM87757 L16464 AAA60949 XM_006711210 XP_006711273 NM_001145312 NP_001138784 NM_005240 NP_005231 |
Function | Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity. {ECO:0000269|PubMed:12007404}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00237}. |
PE-1 CRISPR/Cas9 KO Plasmid (h) - sc-410775 from Santa Cruz Biotechnology
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PE-1 HDR Plasmid (h) - sc-410775-HDR from Santa Cruz Biotechnology
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PE-1 Double Nickase Plasmid (h) - sc-410775-NIC from Santa Cruz Biotechnology
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PE-1 Double Nickase Plasmid (h2) - sc-410775-NIC-2 from Santa Cruz Biotechnology
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PE-1 CRISPR Activation Plasmid (h) - sc-410775-ACT from Santa Cruz Biotechnology
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PE-1 CRISPR Activation Plasmid (h2) - sc-410775-ACT-2 from Santa Cruz Biotechnology
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PE-1 Lentiviral Activation Particles (h) - sc-410775-LAC from Santa Cruz Biotechnology
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PE-1 Lentiviral Activation Particles (h2) - sc-410775-LAC-2 from Santa Cruz Biotechnology
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PE-1 siRNA (h) - sc-88114 from Santa Cruz Biotechnology
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PE-1 shRNA Plasmid (h) - sc-88114-SH from Santa Cruz Biotechnology
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PE-1 shRNA (h) Lentiviral Particles - sc-88114-V from Santa Cruz Biotechnology
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ETV3 RNAi - H00002117-R01 from Novus Biologicals
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MISSION® esiRNA - EHU068971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8011 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8011 from Sigma-Aldrich
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ETV3 siRNA (Human) - CRH1470 from Cohesion Biosciences
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ETV3 - MBS8214004 from MyBioSource
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shRNA set against Human ETV3 (NM_005240.1) - SHH287697 from Creative biogene
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shRNA set against Human ETV3(NM_005240.1) - SHH040529 from Creative biogene
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ETV3 shRNA Plasmid (Human) - CHH1470 from Cohesion Biosciences
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ETV3 miRNA 3'UTR clone - MiUTR1H-03326 from Creative biogene
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