Gene Symbol | Cyp7a1 |
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Entrez Gene | 13122 |
Alt Symbol | - |
Species | Mouse |
Gene Type | protein-coding |
Description | cytochrome P450, family 7, subfamily a, polypeptide 1 |
Other Description | CYPVII|cholesterol 7 alpha hydroxylase|cholesterol 7-alpha-hydroxylase|cholesterol 7-alpha-monooxygenase|cytochrome P450 7A1|cytochrome P450, 7a1 |
Swissprots | Q8BFR7 Q64505 |
Accessions | AAA68867 EDL05690 Q64505 AK050020 BAC34033 AK050210 BAC34123 AK050220 BAC34131 AK050260 BAC34150 BC130261 AAI30262 XM_006537603 XP_006537666 XM_006537604 XP_006537667 NM_007824 NP_031850 |
Function | Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis. {ECO:0000269|PubMed:14522988}. |
Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
Top Pathways | Primary bile acid biosynthesis, Steroid hormone biosynthesis, PPAR signaling pathway, Bile secretion |
Mouse Cytochrome P450 7A1 Protein - abx066267 from Abbexa
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Recombinant Cytochrome P450 7A1 (CYP7A1) - RPB053Mu01 from Cloud-clone
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Recombinant Cytochrome P450 7A1 (CYP7A1) - RPB053Mu02 from Cloud-clone
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Recombinant Mouse Cholesterol 7-alpha-monooxygenase(Cyp7a1) - CSB-YP720674MO CSB-EP720674MO CSB-BP720674MO CSB-MP720674MO from Cusabio
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Cytochrome P450 7A1 (CYP7A1) - RPU141135 from Biomatik
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Recombinant Mouse CYP7A1 Protein - CYP7A1-4232M from Creative Biomart
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Recombinant Cytochrome P450 7A1 (CYP7A1) - RPU41135 from Biomatik
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CYP7A1 Recombinant Protein (OPCD02623) - OPCD02623 from Aviva Systems Biology
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Cholesterol 7-alpha-monooxygenase (Cyp7a1), Recombinant Protein - MBS1427844 from MyBioSource
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Cytochrome P450 7A1 (CYP7A1), Recombinant Protein - MBS2018469 from MyBioSource
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