Gene Symbol |
CHRFAM7A
|
Entrez Gene |
89832
|
Alt Symbol |
CHRNA7, CHRNA7-DR1, D-10
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
|
Other Description |
CHRNA7 (cholinergic receptor, nicotinic, alpha polypeptide 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion|CHRNA7-FAM7A fusion protein|alpha 7 neuronal nicotinic acetylcholine receptor-FAM7A hybrid|alpha-7 nicotinic cholinergic receptor subunit
|
Swissprots |
Q99555 Q494W8 B4DFS0 A8KAB9 A8K7Q4 P36544 Q15826 Q8IUZ4 Q96RH2 Q9BXH0
|
Accessions |
Q494W8 AF029838 AF029839 AF036903 AF037646 AK292984 BAF85673 BC101345 AAI01346 BC101346 AAI01347 BC101347 AAI01348 BC101348 AAI01349 BQ720423 HG506823 XM_005254750 XP_005254807 XM_006725563 XP_006725626 XM_011522153 XP_011520455 XM_011522154 XP_011520456 XM_011522155 XP_011520457 XM_011547425 XP_011545727 XM_011548967 XP_011547269 XM_011548968 XP_011547270 NM_139320 NP_647536 NM_148911 NP_683709
|
Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
|
Subcellular Location |
Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Tissue Specificity |
Expressed in hippocampus. {ECO:0000269|PubMed:9782083}.
|