Gene Symbol | CHRFAM7A |
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Entrez Gene | 89832 |
Alt Symbol | CHRNA7, CHRNA7-DR1, D-10 |
Species | Human |
Gene Type | protein-coding |
Description | CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion |
Other Description | CHRNA7 (cholinergic receptor, nicotinic, alpha polypeptide 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion|CHRNA7-FAM7A fusion protein|alpha 7 neuronal nicotinic acetylcholine receptor-FAM7A hybrid|alpha-7 nicotinic cholinergic receptor subunit |
Swissprots | Q99555 Q494W8 B4DFS0 A8KAB9 A8K7Q4 P36544 Q15826 Q8IUZ4 Q96RH2 Q9BXH0 |
Accessions | Q494W8 AF029838 AF029839 AF036903 AF037646 AK292984 BAF85673 BC101345 AAI01346 BC101346 AAI01347 BC101347 AAI01348 BC101348 AAI01349 BQ720423 HG506823 XM_005254750 XP_005254807 XM_006725563 XP_006725626 XM_011522153 XP_011520455 XM_011522154 XP_011520456 XM_011522155 XP_011520457 XM_011547425 XP_011545727 XM_011548967 XP_011547269 XM_011548968 XP_011547270 NM_139320 NP_647536 NM_148911 NP_683709 |
Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin. |
Subcellular Location | Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed in hippocampus. {ECO:0000269|PubMed:9782083}. |
CHRFAM7A CRISPR/Cas9 KO Plasmid (h) - sc-417317 from Santa Cruz Biotechnology
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CHRFAM7A HDR Plasmid (h) - sc-417317-HDR from Santa Cruz Biotechnology
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CHRFAM7A Double Nickase Plasmid (h) - sc-417317-NIC from Santa Cruz Biotechnology
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CHRFAM7A Double Nickase Plasmid (h2) - sc-417317-NIC-2 from Santa Cruz Biotechnology
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CHRFAM7A CRISPR Activation Plasmid (h) - sc-417317-ACT from Santa Cruz Biotechnology
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CHRFAM7A CRISPR Activation Plasmid (h2) - sc-417317-ACT-2 from Santa Cruz Biotechnology
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CHRFAM7A Lentiviral Activation Particles (h) - sc-417317-LAC from Santa Cruz Biotechnology
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CHRFAM7A Lentiviral Activation Particles (h2) - sc-417317-LAC-2 from Santa Cruz Biotechnology
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CHRFAM7A siRNA (h) - sc-105204 from Santa Cruz Biotechnology
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CHRFAM7A shRNA Plasmid (h) - sc-105204-SH from Santa Cruz Biotechnology
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CHRFAM7A shRNA (h) Lentiviral Particles - sc-105204-V from Santa Cruz Biotechnology
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CHRFAM7A RNAi - H00089832-R01 from Novus Biologicals
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Nicotinic Acetylcholine R alpha 7/CHRNA7 RNAi - H00001139-R01 from Novus Biologicals
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CHRFAM7A RNAi - H00089832-R02 from Novus Biologicals
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MISSION® esiRNA - EHU113741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6090 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6090 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08053 from Sigma-Aldrich
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CHRFAM7A siRNA (Human) - CRJ3863 from Cohesion Biosciences
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CHRFAM7A - MBS8238577 from MyBioSource
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shRNA set against Human CHRFAM7A (NM_148911.1) - SHH263441 from Creative biogene
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shRNA set against Human CHRFAM7A(NM_139320.1) - SHG176441 from Creative biogene
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shRNA set against Human CHRFAM7A(NM_148911.1) - SHG176587 from Creative biogene
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Human CHRFAM7A siRNA - orb274364 from Biorbyt
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CHRFAM7A shRNA Plasmid (Human) - CHJ3863 from Cohesion Biosciences
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