RAB3IP

Gene Symbol	RAB3IP
Entrez Gene	117177
Alt Symbol	RABIN3, RABIN8
Species	Human
Gene Type	protein-coding
Description	RAB3A interacting protein
Other Description	SSX2 interacting protein|SSX2-interacting protein|rab-3A-interacting protein|rab3A-interacting protein|rabin-3
Swissprots	B7WPJ6 Q96QE6 Q96A24 Q96QF1 Q96QE8 Q96QE7 Q9H673 Q96QE9 Q96QF0 Q6PCE4
Accessions	EAW97237 EAW97238 EAW97239 EAW97240 EAW97241 EAW97242 Q96QF0 AI912718 AJ312896 CAC59835 AJ312897 CAC59836 AJ312898 CAC59837 AJ312899 CAC59838 AJ312900 CAC59839 AJ312901 CAC59840 AK026201 BAB15391 AK027566 BAB55202 AK027671 BAB55283 AK057844 AK123728 AK225441 AK314547 AY685922 AAT94123 BC014553 BC015548 AAH15548 BC059358 AAH59358 BX537658 DA211792 DA874650 DB460944 DN912041 HQ448523 ADQ33002 XM_006719226 XP_006719289 XM_006719227 XP_006719290 XM_011537867 XP_011536169 XR_944487 XR_944488 XR_944489 XR_944490 XR_944491 XR_944492 NM_175626 NM_175627 NM_001024647 NP_001019818 NM_001278402 NP_001265331 NM_022456 NP_071901 NM_175623 NP_783322 NM_175624 NP_783323 NM_175625 NP_783324 NR_103519 NR_103520
Function	Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. {ECO:0000269|PubMed:12221131, ECO:0000269|PubMed:20890297, ECO:0000269|PubMed:20937701}.
Subcellular Location	Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Note=Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus. Activation of protein kinase C results in redistribution to the periphery of lamellipodia. In the cytoskeleton, localizes to cortical actin.
Tissue Specificity	Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or liver. {ECO:0000269|PubMed:12007189, ECO:0000269|PubMed:12221131}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RAB3IP 293T Cell Transient Overexpression Lysate(Denatured) - H00117177-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

RAB3IP overexpression lysate - LY406273 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

RAB3IP overexpression lysate - LY411671 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

RAB3IP overexpression lysate - LY422524 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

RAB3IP 293 Cell Lysate - 409746 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

RAB3IP 293 Cell Lysate - 405829 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

RAB3IP Overexpression Lysate (Native) - NBL1-15075 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

RAB3IP Overexpression Lysate (Native) - NBP2-06434 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

RAB3IP Over-expression Lysate Product - GWB-5B0D1F from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

RAB3IP Over-expression Lysate Product - GWB-140DE7 from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

RAB3IP Overexpression Lysate (Denatured) - H00117177-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human RAB3IP Knockdown Stable Cell Line - CSC-DC012861 from Creative biogene Category Cell Line Species Human

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