RAB3IP

Gene Symbol RAB3IP
Entrez Gene 117177
Alt Symbol RABIN3, RABIN8
Species Human
Gene Type protein-coding
Description RAB3A interacting protein
Other Description SSX2 interacting protein|SSX2-interacting protein|rab-3A-interacting protein|rab3A-interacting protein|rabin-3
Swissprots B7WPJ6 Q96QE6 Q96A24 Q96QF1 Q96QE8 Q96QE7 Q9H673 Q96QE9 Q96QF0 Q6PCE4
Accessions EAW97237 EAW97238 EAW97239 EAW97240 EAW97241 EAW97242 Q96QF0 AI912718 AJ312896 CAC59835 AJ312897 CAC59836 AJ312898 CAC59837 AJ312899 CAC59838 AJ312900 CAC59839 AJ312901 CAC59840 AK026201 BAB15391 AK027566 BAB55202 AK027671 BAB55283 AK057844 AK123728 AK225441 AK314547 AY685922 AAT94123 BC014553 BC015548 AAH15548 BC059358 AAH59358 BX537658 DA211792 DA874650 DB460944 DN912041 HQ448523 ADQ33002 XM_006719226 XP_006719289 XM_006719227 XP_006719290 XM_011537867 XP_011536169 XR_944487 XR_944488 XR_944489 XR_944490 XR_944491 XR_944492 NM_175626 NM_175627 NM_001024647 NP_001019818 NM_001278402 NP_001265331 NM_022456 NP_071901 NM_175623 NP_783322 NM_175624 NP_783323 NM_175625 NP_783324 NR_103519 NR_103520
Function Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. {ECO:0000269|PubMed:12221131, ECO:0000269|PubMed:20890297, ECO:0000269|PubMed:20937701}.
Subcellular Location Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Note=Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus. Activation of protein kinase C results in redistribution to the periphery of lamellipodia. In the cytoskeleton, localizes to cortical actin.
Tissue Specificity Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or liver. {ECO:0000269|PubMed:12007189, ECO:0000269|PubMed:12221131}.

RAB3IP (G-15) - sc-162067 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RAB3IP (S-14) - sc-162069 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-RAB3IP antibody - ab90732 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Primary Antibody Dilution : 1:200. Secondary Antibody : Goat anti-rabbit Alexafluor 568. Secondary Antibody Dilution : 1:200. Color/Signal Descriptions : RAB3IP: Red CtBp: Green DAPI: Blue. Gene Name : RAB3IP.

Anti-RAB3IP antibody - ab94455 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Species + tissue type: Mouse retina tissue. Primary antibody dilution: 1:200. Secondary antibody: Goat anti-rabbit Alexafluor 568. Secondary antibody dilution: 1:200

Anti-RAB3IP antibody - ab197206 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RAB3IP antibody (ab197206) at 1/500 dilutionLane 1 : Human fetal kidney lysateLane 2 : Human fetal heart lysate

Anti-RAB3IP antibody - ab168525 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-RAB3IP antibody (ab168525) at 1 µg/mlLane 1 : RAB3IP transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysate

Anti-RAB3IP / RABIN3 Antibody (aa257-306) - LS-C120290 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human brain tissue, using RAB3IP Antibody. The picture on the right is treated with the synthesized peptide.

Anti-RAB3IP / RABIN3 Antibody (aa107-156) - LS-C111504 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RAB3IP antibody LS-C111504 Western blot of NCI-H226 cell lysate.

Anti-RAB3IP / RABIN3 Antibody (aa35-84) - LS-C111503 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RAB3IP antibody LS-C111503 Western blot of 293T cell lysate.

RAB3IP Antibody - NBP1-56745 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RAB3IP Antibody [NBP1-56745] - Reccomended Titration: 0.2 - 1 ug/ml ELISA Titer: 1:312500 Positive Control: NCI-H226 cell lysate

RAB3IP Antibody - NBP1-56744 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: RAB3IP Antibody [NBP1-56744] - Titration: 0.2-1 ug/ml, Positive Control: 293T cell lysate.

RAB3IP Antibody - NBP1-92309 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RAB3IP Antibody [NBP1-92309] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue

RAB3IP Antibody - H00117177-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: RAB3IP Antibody [H00117177-B01P] - Analysis of RAB3IP expression in rat brain.

Anti-RAB3IP antibody produced in rabbit - SAB4500274 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RAB3IP: <B>Cat. No. SAB4500274</B>: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-RAB3IP antibody. Cells on the left were treated with the Anti-RAB3IP antibody. Cells on the right (negative control) were treated with both Anti-RAB3IP antibody and the synthesized immunogen peptide.

Anti-RAB3IP antibody produced in mouse - SAB1408855 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RAB3IP: <B>Cat. No. SAB1408855</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~50.6 kDa using RAB3IP transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-RAB3IP antibody produced in rabbit - HPA039794 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RAB3IP: <B>Cat. No. HPA039794</B>: Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in pancreatic ductal cells.

Anti-RAB3IP, (N-terminal) antibody produced in rabbit - SAB2104375 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RAB3IP, antibody produced in rabbit: <B>Cat. No. SAB2104375</B>: Immunoblotting analysis of RAB3IP in NCI-H226 cell lysate with RAB3IP anitbody at 1 μg/mL.

Anti-RAB3IP (96-110) antibody produced in rabbit - SAB1102743 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human RAB3IP was separated on SDS-PAGE, blotted with Anti-RAB3IP (96-110) (<B>Cat. No. SAB1102743</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000

RAB3IP antibody - N-terminal region (ARP53319_P050) - ARP53319_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RAB3IP antibody - N-terminal region (ARP53320_P050) - ARP53320_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RAB3IP Antibody (OAAF04115) - OAAF04115 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

RAB3IP antibody - 70R-4196 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

RAB3IL1 antibody - 70R-3159 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

RAB3IP antibody - 70R-19714 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

RAB3IP antibody - 12321-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Human brain were subjected to SDS PAGE followed by western blot with 12321-1-AP(RAB3IP Antibody) at dilution of 1:1000
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