ZNF207

Gene Symbol	ZNF207
Entrez Gene	7756
Alt Symbol	BuGZ
Species	Human
Gene Type	protein-coding
Description	zinc finger protein 207
Other Description	BUB3-interacting and GLEBS motif-containing protein ZNF207
Swissprots	Q9BUQ7 E1P660 Q53XS9 Q96HW5 O43670 E1P662 E1P661 A8K6Y6
Accessions	EAW80231 EAW80232 EAW80233 EAW80234 EAW80235 EAW80236 EAW80237 O43670 AB209215 BAD92452 AF046001 AAC78561 AI308956 AK026215 AK226172 AK291801 BAF84490 AK298950 BAG61049 AK309979 AL834501 CAD39159 BC000962 BC002372 AAH02372 BC008023 AAH08023 BT007365 AAP36029 CN276833 JF432111 ADZ15328 XM_005258029 XP_005258086 XM_011525185 XP_011523487 XR_934542 XR_934543 XR_934544 NM_001032293 NP_001027464 NM_001098507 NP_001091977 NM_003457 NP_003448
Function	Kinetochore-binding protein involved in spindle-assembly checkpoint signaling by regulating mitotic chromosome alignment and mediating the stability and kinetochore loading of BUB3. Mechanisms by which BUB3 is protected are unclear: according to a first report, ZNF207/BuGZ may act by blocking ubiquitination and proteasomal degradation of BUB3 (PubMed:24462186). According to another report, the stabilization is independent of the proteasome (PubMed:24462187). {ECO:0000269|PubMed:24462186, ECO:0000269|PubMed:24462187}.
Subcellular Location	Nucleus. Chromosome, centromere, kinetochore. Note=Localizes primarily to the nucleus in interphase, concentrates at kinetochores prior to nuclear envelope breakdown and during early prometaphase, and disappears from kinetochores upon microtubule-binding.
Tissue Specificity	Ubiquitous.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ZNF207 CRISPR/Cas9 KO Plasmid (h) - sc-408389 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ZNF207 HDR Plasmid (h) - sc-408389-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ZNF207 Double Nickase Plasmid (h) - sc-408389-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ZNF207 Double Nickase Plasmid (h2) - sc-408389-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ZNF207 CRISPR Activation Plasmid (h) - sc-408389-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ZNF207 CRISPR Activation Plasmid (h2) - sc-408389-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ZNF207 Lentiviral Activation Particles (h) - sc-408389-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ZNF207 Lentiviral Activation Particles (h2) - sc-408389-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ZNF207 siRNA (h) - sc-93847 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ZNF207 shRNA Plasmid (h) - sc-93847-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ZNF207 shRNA (h) Lentiviral Particles - sc-93847-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ZNF207 RNAi - H00007756-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

ZNF207 RNAi - H00007756-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU061721 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23306 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23306 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

ZNF207 siRNA (Human) - CRH5250 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ZNF207 RNAi - H00007756-R01 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

ZNF207 - MBS8207237 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ZNF207 (NM_003457.3) - SHH453280 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ZNF207(NM_001032293.2) - SHL155592 from Creative biogene Category siRNA Species Reactivities Human

ZNF207 shRNA Plasmid (Human) - CHH5250 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ZNF207 miRNA 3'UTR clone - MiUTR1H-11509 from Creative biogene Species Reactivities Human

ZNF207 miRNA 3'UTR clone - MiUTR1H-11510 from Creative biogene Species Reactivities Human

ZNF207 miRNA 3'UTR clone - MiUTR3H-05960 from Creative biogene Species Reactivities Human

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