Gene Symbol |
MRTO4
|
Entrez Gene |
51154
|
Alt Symbol |
C1orf33, MRT4, dJ657E11.4
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
mRNA turnover 4 homolog (S. cerevisiae)
|
Other Description |
60S acidic ribosomal protein PO|MRT4, mRNA turnover 4, homolog|mRNA turnover protein 4 homolog|ribosome assembly factor MRTO4
|
Swissprots |
Q9BPV9 Q96SS6 Q5TG55 Q9UKD2 B3KNB3
|
Accessions |
EAW94873 EAW94874 EAW94875 Q9UKD2 AF173378 AAD52608 AK024227 BAG51275 AK027569 BAB55205 AK295328 BAG58304 AY303790 AAP68821 BC003013 AAH03013 BC006504 AAH06504 BP312953 BQ670859 XM_006710675 XP_006710738 NM_016183 NP_057267
|
Function |
Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. {ECO:0000269|PubMed:20083226}.
|
Subcellular Location |
Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:20083226}. Cytoplasm {ECO:0000269|PubMed:20083226}. Note=Shutles between the nucleus and the cytoplasm. {ECO:0000269|PubMed:20083226}.
|