Gene Symbol | MRTO4 |
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Entrez Gene | 51154 |
Alt Symbol | C1orf33, MRT4, dJ657E11.4 |
Species | Human |
Gene Type | protein-coding |
Description | mRNA turnover 4 homolog (S. cerevisiae) |
Other Description | 60S acidic ribosomal protein PO|MRT4, mRNA turnover 4, homolog|mRNA turnover protein 4 homolog|ribosome assembly factor MRTO4 |
Swissprots | Q9BPV9 Q96SS6 Q5TG55 Q9UKD2 B3KNB3 |
Accessions | EAW94873 EAW94874 EAW94875 Q9UKD2 AF173378 AAD52608 AK024227 BAG51275 AK027569 BAB55205 AK295328 BAG58304 AY303790 AAP68821 BC003013 AAH03013 BC006504 AAH06504 BP312953 BQ670859 XM_006710675 XP_006710738 NM_016183 NP_057267 |
Function | Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. {ECO:0000269|PubMed:20083226}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:20083226}. Cytoplasm {ECO:0000269|PubMed:20083226}. Note=Shutles between the nucleus and the cytoplasm. {ECO:0000269|PubMed:20083226}. |
MRT4 CRISPR/Cas9 KO Plasmid (h) - sc-412132 from Santa Cruz Biotechnology
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MRT4 HDR Plasmid (h) - sc-412132-HDR from Santa Cruz Biotechnology
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MRT4 Double Nickase Plasmid (h) - sc-412132-NIC from Santa Cruz Biotechnology
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MRT4 Double Nickase Plasmid (h2) - sc-412132-NIC-2 from Santa Cruz Biotechnology
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MRT4 CRISPR Activation Plasmid (h) - sc-412132-ACT from Santa Cruz Biotechnology
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MRT4 CRISPR Activation Plasmid (h2) - sc-412132-ACT-2 from Santa Cruz Biotechnology
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MRT4 Lentiviral Activation Particles (h) - sc-412132-LAC from Santa Cruz Biotechnology
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MRT4 Lentiviral Activation Particles (h2) - sc-412132-LAC-2 from Santa Cruz Biotechnology
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MRT4 siRNA (h) - sc-88180 from Santa Cruz Biotechnology
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MRT4 shRNA Plasmid (h) - sc-88180-SH from Santa Cruz Biotechnology
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MRT4 shRNA (h) Lentiviral Particles - sc-88180-V from Santa Cruz Biotechnology
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MRTO4 RNAi - H00051154-R01 from Novus Biologicals
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MISSION® esiRNA - EHU009541 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14625 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14625 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08880 from Sigma-Aldrich
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MRTO4 siRNA (Human) - CRH9567 from Cohesion Biosciences
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shRNA set against Human MRTO4 (NM_016183.3) - SHH345412 from Creative biogene
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shRNA set against Human MRTO4(NM_016183.3) - SHH202727 from Creative biogene
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MRTO4 shRNA Plasmid (Human) - CHH9567 from Cohesion Biosciences
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MRTO4 miRNA 3'UTR clone - MiUTR1H-06461 from Creative biogene
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