Gene Symbol | RGS19 |
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Entrez Gene | 10287 |
Alt Symbol | GAIP, RGSGAIP |
Species | Human |
Gene Type | protein-coding |
Description | regulator of G-protein signaling 19 |
Other Description | G alpha interacting protein|G protein signalling regulator 19|G-alpha-interacting protein|guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein|regulator of G-protein signalling 19 |
Swissprots | Q53XN0 P49795 E1P5G9 A8K216 Q8TD60 |
Accessions | AAG42352 EAW75166 EAW75167 P49795 AF285096 AF285097 AF493939 AAM12653 AK290081 BAF82770 AK298240 BAG60506 AY585188 AAS94232 BC001318 AAH01318 BC054337 AAH54337 BC063010 AAH63010 BM554550 BT009804 AAP88806 CR457430 CAG33711 DQ891204 ABM82130 DQ894387 ABM85313 X91809 CAA62919 XM_005260182 XP_005260239 XM_005260183 XP_005260240 XM_011528484 XP_011526786 XM_011528485 XP_011526787 XM_011528486 XP_011526788 NM_005873 NP_005864 NM_001039467 NP_001034556 |
Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein. |
Subcellular Location | Membrane; Lipid-anchor. |
Tissue Specificity | Highest expression in lung. Placenta, liver and heart also express high levels of GAIP. |
Human RGS19 full length protein - ab75333 from Abcam
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Human RGS19 full length protein - ab101949 from Abcam
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RGS19 Antibody Blocking Peptide - LS-E5675 from LifeSpan Bioscience
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RGS19 Antibody Blocking Peptide - LS-E12034 from LifeSpan Bioscience
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RGS19 Antibody Blocking Peptide - LS-E7364 from LifeSpan Bioscience
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RGS19 Antibody Blocking Peptide - LS-E21564 from LifeSpan Bioscience
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RGS19 Recombinant Protein - H00010287-P01 from Novus Biologicals
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RGS19 Partial Recombinant Protein - H00010287-Q01 from Novus Biologicals
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Recombinant Human RGS19 Protein - NBP1-50894 from Novus Biologicals
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RGS19 Peptide - P1531 from Novus Biologicals
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RGS19 Peptide - P1525 from Novus Biologicals
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RGS19-Antibody-S151-Blocking-Peptide - BP1820f from Abgent, a WuXi AppTec company
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RGS19-Antibody-N-term-Blocking-Peptide - BP1820a from Abgent, a WuXi AppTec company
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Phospho-RGS19S24-Antibody-Blocking-peptide - BP3396a from Abgent, a WuXi AppTec company
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Phospho-RGS19-S22-Antibody-Blocking-Peptide - BP3388a from Abgent, a WuXi AppTec company
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RGS19 Protein Lysate (APL11081) - APL11081 from Aviva Systems Biology
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RGS19 Protein (OPPA02569) - OPPA02569 from Aviva Systems Biology
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Human RGS19 protein - orb169186 from Biorbyt
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RGS19 Blocking Peptide - 33R-3712 from Fitzgerald
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RGS19 Blocking Peptide - 33R-7391 from Fitzgerald
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RGS19 protein (His tag) - 80R-1571 from Fitzgerald
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RGS19 (1-217, His-tag) - AR09750PU-L from Acris Antibodies
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RGS19 (1-217, His-tag) - AR09750PU-N from Acris Antibodies
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RGS19 - H00010287-P01-10 from Acris Antibodies
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RGS19 - H00010287-P01-25 from Acris Antibodies
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