CLCA4

Gene Symbol CLCA4
Entrez Gene 22802
Alt Symbol CaCC, CaCC2
Species Human
Gene Type protein-coding
Description chloride channel accessory 4
Other Description caCC-2|calcium-activated chloride channel family member 4|calcium-activated chloride channel protein 2|calcium-activated chloride channel regulator 4|chloride channel regulator 4|chloride channel, calcium activated, family member 4|hCLCA4|hCaCC-2
Swissprots Q6UX81 Q14CN2 Q9UNF7 A8MQC9 B7Z1Q5
Accessions CCQ43402 EAW73184 EAW73185 Q14CN2 AF127035 AAD48398 AK000072 AK000138 BAA90969 AK293766 BAH11591 AK307785 AK307898 AK314430 AY358470 AAQ88834 BC113687 AAI13688 BC113689 AAI13690 CB851641 DA668017 DA761219 HQ258531 ADR83285 XM_011541015 XP_011539317 NM_012128 NP_036260 NR_024602
Function May be involved in mediating calcium-activated chloride conductance.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Apical cell membrane {ECO:0000250}. Secreted {ECO:0000250}. Note=The C-terminus 30 kDa form is anchored to the membrane. The N-terminus 110 kDa form is released from the membrane triggered by an unknown stimulus. {ECO:0000250}.
Tissue Specificity Primarily expressed in the digestive tract, mainly in colon. Detected in smaller amounts in brain, urogenital organs, testis, and salivary and mammary glands. Highly expressed in the epithelial layer and submucosal gland of the inferior turbinate mucosa. Lower levels in the epithelial layer of nasal polyp. {ECO:0000269|PubMed:10437792, ECO:0000269|PubMed:15490240, ECO:0000269|PubMed:16012037}.
Top Pathways Olfactory transduction, Pancreatic secretion

CLCA4 CRISPR/Cas9 KO Plasmid (h) - sc-411607 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLCA4 HDR Plasmid (h) - sc-411607-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLCA4 Double Nickase Plasmid (h) - sc-411607-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLCA4 Double Nickase Plasmid (h2) - sc-411607-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLCA4 CRISPR Activation Plasmid (h) - sc-411607-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLCA4 CRISPR Activation Plasmid (h2) - sc-411607-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLCA4 Lentiviral Activation Particles (h) - sc-411607-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLCA4 Lentiviral Activation Particles (h2) - sc-411607-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLCA4 siRNA (h) - sc-105212 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLCA4 shRNA Plasmid (h) - sc-105212-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLCA4 shRNA (h) Lentiviral Particles - sc-105212-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLCA4 RNAi - H00022802-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU040231 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6166 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6166 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CLCA4 siRNA (Human) - CRH7781 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLCA4 - MBS8230693 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CLCA4 (NM_012128.3) - SHH264519 from Creative biogene

Category siRNA
Species Reactivities Human

CLCA4 shRNA Plasmid (Human) - CHH7781 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CLCA4 miRNA 3'UTR clone - MiUTR1H-02180 from Creative biogene

Species Reactivities Human
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