Gene Symbol | VBP1 |
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Entrez Gene | 7411 |
Alt Symbol | HIBBJ46, PFD3, PFDN3, VBP-1 |
Species | Human |
Gene Type | protein-coding |
Description | von Hippel-Lindau binding protein 1 |
Other Description | VHL binding protein-1|prefoldin subunit 3 |
Swissprots | Q86X96 Q5JT81 B2R8L5 P61758 O55228 Q15765 |
Accessions | CAI41469 EAW72627 EAW72628 EAW72629 EAW72630 P61758 AA626259 AA781721 AK301646 BAG63125 AK313420 BAG36212 BC009570 BC040002 BC046094 AAH46094 BG575380 BT019604 AAV38411 CR541932 CAG46730 DA610631 U56833 AAC50617 U96759 AAC23907 Y17394 CAA76761 NM_001303543 NP_001290472 NM_001303544 NP_001290473 NM_001303545 NP_001290474 NM_003372 NP_003363 |
Function | Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. {ECO:0000269|PubMed:9630229}. |
Subcellular Location | Cytoplasm. Nucleus. Note=In complex with VHL can translocate to the nucleus. |
Tissue Specificity | Ubiquitous. |
prefoldin 3 CRISPR/Cas9 KO Plasmid (h) - sc-405482 from Santa Cruz Biotechnology
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prefoldin 3 HDR Plasmid (h) - sc-405482-HDR from Santa Cruz Biotechnology
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prefoldin 3 Double Nickase Plasmid (h) - sc-405482-NIC from Santa Cruz Biotechnology
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prefoldin 3 Double Nickase Plasmid (h2) - sc-405482-NIC-2 from Santa Cruz Biotechnology
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prefoldin 3 CRISPR Activation Plasmid (h) - sc-405482-ACT from Santa Cruz Biotechnology
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prefoldin 3 CRISPR Activation Plasmid (h2) - sc-405482-ACT-2 from Santa Cruz Biotechnology
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prefoldin 3 Lentiviral Activation Particles (h) - sc-405482-LAC from Santa Cruz Biotechnology
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prefoldin 3 Lentiviral Activation Particles (h2) - sc-405482-LAC-2 from Santa Cruz Biotechnology
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prefoldin 3 siRNA (h) - sc-40873 from Santa Cruz Biotechnology
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prefoldin 3 shRNA Plasmid (h) - sc-40873-SH from Santa Cruz Biotechnology
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prefoldin 3 shRNA (h) Lentiviral Particles - sc-40873-V from Santa Cruz Biotechnology
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VBP1 RNAi - H00007411-R01 from Novus Biologicals
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MISSION® esiRNA - EHU034711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22652 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22652 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12432 from Sigma-Aldrich
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VBP1 siRNA (Human) - CRH5070 from Cohesion Biosciences
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VBP1 - MBS8203702 from MyBioSource
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shRNA set against Human VBP1 (NM_003372.5) - SHH442412 from Creative biogene
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Human VBP1 siRNA - orb265572 from Biorbyt
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VBP1 shRNA Plasmid (Human) - CHH5070 from Cohesion Biosciences
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VBP1 miRNA 3'UTR clone - MiUTR3H-02582 from Creative biogene
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