| Gene Symbol | ABCB10 |
|---|---|
| Entrez Gene | 23456 |
| Alt Symbol | EST20237, M-ABC2, MTABC2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATP-binding cassette, sub-family B (MDR/TAP), member 10 |
| Other Description | ABC transporter 10 protein|ATP-binding cassette sub-family B member 10, mitochondrial|ATP-binding cassette transporter 10|mitochondrial ATP-binding cassette 2 |
| Swissprots | Q6P1Q8 Q13040 Q9NRK6 Q9H3V0 |
| Accessions | EAW69901 Q9NRK6 AB013380 BAB20265 AF216833 AAF78198 AF277184 AAK07543 AK172794 BAD18770 BC064930 AAH64930 DQ786241 U18237 AAA84438 XM_011544135 XP_011542437 XM_011544136 XP_011542438 NM_012089 NP_036221 |
| Function | May mediate critical mitochondrial transport functions related to heme biosynthesis. {ECO:0000250}. |
| Subcellular Location | Mitochondrion inner membrane; Multi-pass membrane protein. |
| Tissue Specificity | Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon. |
| Top Pathways | ABC transporters |
ABCB10 overexpression lysate - LY415992 from Acris Antibodies
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ABCB10 Overexpression Lysate (Native) - NBP2-07495 from Novus Biologicals
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Panoply™ Human ABCB10 Knockdown Stable Cell Line - CSC-DC000041 from Creative biogene
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