Gene Symbol | ABCB10 |
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Entrez Gene | 23456 |
Alt Symbol | EST20237, M-ABC2, MTABC2 |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family B (MDR/TAP), member 10 |
Other Description | ABC transporter 10 protein|ATP-binding cassette sub-family B member 10, mitochondrial|ATP-binding cassette transporter 10|mitochondrial ATP-binding cassette 2 |
Swissprots | Q6P1Q8 Q13040 Q9NRK6 Q9H3V0 |
Accessions | EAW69901 Q9NRK6 AB013380 BAB20265 AF216833 AAF78198 AF277184 AAK07543 AK172794 BAD18770 BC064930 AAH64930 DQ786241 U18237 AAA84438 XM_011544135 XP_011542437 XM_011544136 XP_011542438 NM_012089 NP_036221 |
Function | May mediate critical mitochondrial transport functions related to heme biosynthesis. {ECO:0000250}. |
Subcellular Location | Mitochondrion inner membrane; Multi-pass membrane protein. |
Tissue Specificity | Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon. |
Top Pathways | ABC transporters |
ABC-me CRISPR/Cas9 KO Plasmid (h) - sc-405808 from Santa Cruz Biotechnology
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ABC-me HDR Plasmid (h) - sc-405808-HDR from Santa Cruz Biotechnology
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ABC-me Double Nickase Plasmid (h) - sc-405808-NIC from Santa Cruz Biotechnology
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ABC-me Double Nickase Plasmid (h2) - sc-405808-NIC-2 from Santa Cruz Biotechnology
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ABC-me CRISPR Activation Plasmid (h) - sc-405808-ACT from Santa Cruz Biotechnology
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ABC-me CRISPR Activation Plasmid (h2) - sc-405808-ACT-2 from Santa Cruz Biotechnology
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ABC-me Lentiviral Activation Particles (h) - sc-405808-LAC from Santa Cruz Biotechnology
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ABC-me Lentiviral Activation Particles (h2) - sc-405808-LAC-2 from Santa Cruz Biotechnology
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ABC-me siRNA (h) - sc-41155 from Santa Cruz Biotechnology
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ABC-me shRNA Plasmid (h) - sc-41155-SH from Santa Cruz Biotechnology
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ABC-me shRNA (h) Lentiviral Particles - sc-41155-V from Santa Cruz Biotechnology
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ABCB10 RNAi - H00023456-R02 from Novus Biologicals
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MISSION® esiRNA - EHU047911 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2627 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2627 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09824 from Sigma-Aldrich
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ABCB10 siRNA (Human) - CRH8280 from Cohesion Biosciences
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ABCB10 - MBS8236164 from MyBioSource
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shRNA set against Human Abcb10 (NM_012089.2) - SHH228958 from Creative biogene
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Human ABCB10 siRNA - orb268782 from Biorbyt
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ABCB10 shRNA Plasmid (Human) - CHH8280 from Cohesion Biosciences
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ABCB10 miRNA 3'UTR clone - MiUTR3H-07689 from Creative biogene
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