| Gene Symbol |
MPK4
|
| Entrez Gene |
828151
|
| Alt Symbol |
ATMPK4, F2N1.1, F2N1_1, MAP kinase 4
|
| Species |
Arabidopsis thaliana
|
| Gene Type |
protein-coding
|
| Description |
mitogen-activated protein kinase 4
|
| Other Description |
-
|
| Swissprots |
Q9M136 Q45V20 B2BDE6 O04597 B2BDG2 Q39024 B2BDE8 B2BDE5
|
| Accessions |
AAZ20637 ABR46145 ABR46149 ABR46150 ABR46152 ABR46153 ABR46154 ABR46157 ABR46158 ABR46159 ABR46160 ABR46163 AEE82016 CAB80946 CAC43513 Q39024 AF360231 AAK25941 AY040031 AAK64089 AY088537 AAM66070 NM_116367 NP_192046
|
| Function |
The ANPs-MKK6-MPK4 module is involved in the regulation of plant cytokinesis during meiosis and mitosis. Essential to promote the progression of cytokinesis and for cellularization (formation of the cell plate) during male-specific meiotic. Involved in cortical microtubules organization and stabilization by regulating the phosphorylation state of microtubule-associated proteins such as MAP65-1. Involved in root hair development process. Negative regulator of systemic acquired resistance (SAR) and salicylic acid- (SA) mediated defense response. Required for jasmonic acid- (JA) mediated defense gene expression. May regulate activity of transcription factor controlling pathogenesis-related (PR) gene expression. Seems to act independently of the SAR regulatory protein NPR1 (Nonexpresser of PR1). Phosphorylates MKS1 and transcription factors WRKY25 and WRKY33. The MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abioti
|
| Subcellular Location |
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Note=Translocated into the nucleus in response to phosphorylation (Probable). localized to the cell plate. {ECO:0000305}.
|
| Tissue Specificity |
Ubiquitous. Expressed in the veins and stomatal guard cells of leaf plates, petioles, stem, roots and flowers. {ECO:0000269|PubMed:11163186, ECO:0000269|PubMed:20215588, ECO:0000269|PubMed:21575092}.
|
| Top Pathways |
Plant-pathogen interaction
|
