| Gene Symbol |
MINOS1
|
| Entrez Gene |
440574
|
| Alt Symbol |
C1orf151, MIO10
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mitochondrial inner membrane organizing system 1
|
| Other Description |
MICOS complex subunit MIC10|RP5-1056L3.2|UPF0327 protein C1orf151|mitochondrial inner membrane organizing system protein 1
|
| Swissprots |
Q5TGZ0 Q96G68
|
| Accessions |
EAW94893 Q5TGZ0 AJ711911 AK094318 AK096240 BC009927 AAH09927 BC070388 AAH70388 BG687187 BM784596 CB157536 CB852406 DA523181 DA793500 DB323148 NM_001032363 NP_001027535 NM_001204082 NP_001191011 NM_001204083 NP_001191012 NR_033757 NR_033758
|
| Function |
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. {ECO:0000269|PubMed:22114354}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:22114354}; Single-pass membrane protein {ECO:0000269|PubMed:22114354}. Note=The C-terminus is located in the intermembrane space (By similarity), while the location of the N-terminus has not been determined yet. As some programs predict the presence of 2 closely apposed membrane domains, it has been proposed that the protein may cross the membrane twice and that both termini may face the intermembrane space (PubMed:22114354). {ECO:0000250, ECO:0000269|PubMed:22114354}.
|
![Western Blot: MINOS1 Overexpression Lysate (Adult Normal) [NBP2-11608] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MINOS1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7570_MINOS1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-11608-img0001.jpg)