Gene Symbol | MINOS1 |
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Entrez Gene | 440574 |
Alt Symbol | C1orf151, MIO10 |
Species | Human |
Gene Type | protein-coding |
Description | mitochondrial inner membrane organizing system 1 |
Other Description | MICOS complex subunit MIC10|RP5-1056L3.2|UPF0327 protein C1orf151|mitochondrial inner membrane organizing system protein 1 |
Swissprots | Q5TGZ0 Q96G68 |
Accessions | EAW94893 Q5TGZ0 AJ711911 AK094318 AK096240 BC009927 AAH09927 BC070388 AAH70388 BG687187 BM784596 CB157536 CB852406 DA523181 DA793500 DB323148 NM_001032363 NP_001027535 NM_001204082 NP_001191011 NM_001204083 NP_001191012 NR_033757 NR_033758 |
Function | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. {ECO:0000269|PubMed:22114354}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:22114354}; Single-pass membrane protein {ECO:0000269|PubMed:22114354}. Note=The C-terminus is located in the intermembrane space (By similarity), while the location of the N-terminus has not been determined yet. As some programs predict the presence of 2 closely apposed membrane domains, it has been proposed that the protein may cross the membrane twice and that both termini may face the intermembrane space (PubMed:22114354). {ECO:0000250, ECO:0000269|PubMed:22114354}. |
MINOS1 CRISPR/Cas9 KO Plasmid (h) - sc-417564 from Santa Cruz Biotechnology
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MINOS1 HDR Plasmid (h) - sc-417564-HDR from Santa Cruz Biotechnology
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MINOS1 Double Nickase Plasmid (h) - sc-417564-NIC from Santa Cruz Biotechnology
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MINOS1 Double Nickase Plasmid (h2) - sc-417564-NIC-2 from Santa Cruz Biotechnology
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MINOS1 CRISPR Activation Plasmid (h) - sc-417564-ACT from Santa Cruz Biotechnology
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MINOS1 CRISPR Activation Plasmid (h2) - sc-417564-ACT-2 from Santa Cruz Biotechnology
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MINOS1 Lentiviral Activation Particles (h) - sc-417564-LAC from Santa Cruz Biotechnology
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MINOS1 Lentiviral Activation Particles (h2) - sc-417564-LAC-2 from Santa Cruz Biotechnology
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MINOS1 siRNA (h) - sc-88272 from Santa Cruz Biotechnology
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MINOS1 shRNA Plasmid (h) - sc-88272-SH from Santa Cruz Biotechnology
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MINOS1 shRNA (h) Lentiviral Particles - sc-88272-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN4601 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4601 from Sigma-Aldrich
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MINOS1 siRNA (Human) - CRJ8257 from Cohesion Biosciences
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Human MINOS1 siRNA - orb278758 from Biorbyt
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MINOS1 shRNA Plasmid (Human) - CHJ8257 from Cohesion Biosciences
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