GSK3A

Gene Symbol	GSK3A
Entrez Gene	2931
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	glycogen synthase kinase 3 alpha
Other Description	GSK-3 alpha|glycogen synthase kinase-3 alpha|serine/threonine-protein kinase GSK3A
Swissprots	O14959 P49840
Accessions	AAD11986 EAW57114 EAW57115 P49840 BC027984 AAH27984 BC051865 AAH51865 CR749620 CAH18414 D63424 BAA23608 DQ891014 ABM81940 DQ893329 ABM84255 DQ894195 ABM85121 DQ896624 ABM87623 L40027 AAA62432 NM_019884 NP_063937
Function	Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establish
Top Pathways	Chemokine signaling pathway, Dopaminergic synapse, Non-alcoholic fatty liver disease (NAFLD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GSK3A / GSK3 Alpha ELISA Kit (Sandwich ELISA) - LS-F4363 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.049 ng/ml Range 0.156-10 ng/ml

Rat GSK3A / GSK3 Alpha ELISA Kit (Sandwich ELISA) - LS-F4364 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.227 ng/ml Range 0.156-10 ng/ml

Mouse/Human/Rat GSK3A / GSK3 Alpha ELISA Kit (Cell-Based ELISA) - LS-F2030 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat GSK3A / GSK3 Alpha ELISA Kit (Cell-Based ELISA) - LS-F2029 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat Phospho-GSK3A / GSK3 Alpha (Tyr279/216) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1040 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat Phospho-GSK3A / GSK3 Alpha (Ser21) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1520 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Rat GSK3A / GSK3 Alpha ELISA Kit (Sandwich ELISA) - LS-F11583 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.156-10 ng/ml

Phospho-GSK-3 alpha/beta (S21/S9) DuoSet IC ELISA - DYC2630-2 from R&D Systems Category ELISA Kit Prices $329.00, $649.00 Sizes 1 kit (for 2 Plates), 1 kit (for 5 Plates) Range 156.00 - 10,000 pg/mL

Phospho-GSK-3 alpha/beta (S21/S9) DuoSet IC, 5 Plate - DYC2630-5 from R&D Systems Category ELISA Kit

Human Phospho-GSK-3 alpha (S21) DuoSet IC ELISA, 2 Plate - DYC4125-2 from R&D Systems Category ELISA Kit Prices $329.00 Sizes 1 kit (for 2 Plates) Range 156.00 - 10,000 pg/mL

Human GSK3a ELISA Kit - abx151753 from Abbexa Category ELISA Kit Sensitivity 0.049 ng/ml Range 0.156 ng/ml - 10 ng/ml

Glycogen Synthase Kinase 3 Alpha (GSK3a), Human, ELISA Kit - SEA630Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.049ng/mL Range 0.156-10ng/mL

Glycogen Synthase Kinase 3 Alpha, Human, ELISA Kit - E01G0264 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/mL,

Glycogen synthase kinase-3 alpha, GSK3A, Human, ELISA Kit - E0767h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t

Glycogen Synthase Kinase 3 Alpha, GSK3a, Human, ELISA Kit - E-EL-H2001 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Glycogen Synthase Kinase 3 Alpha, GSK3a, Mouse, ELISA Kit - E-EL-M0586 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 4.688 Range 7.813-500pg/mL

Glycogen Synthase Kinase 3 Alpha, GSK3A, Rat, ELISA Kit - E-EL-R0447 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.375 Range 0.625-40ng/mL

Glycogen Synthase Kinase 3 Alpha, GSK3a, Rabbit, ELISA Kit - E-EL-RB1537 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Glycogen Synthase Kinase 3 Alpha, GSK3a, Chicken, ELISA Kit - E-EL-Ch0359 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Glycogen Synthase Kinase 3 Alpha, GSK3a, Porcine, ELISA Kit - E-EL-P0916 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Glycogen Synthase Kinase 3 Alpha, GSK3a, Sheep, ELISA Kit - E-EL-S0805 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Glycogen Synthase Kinase 3 Alpha, GSK3a, Monkey, ELISA Kit - E-EL-MK0771 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human/Mouse/Rat Phospho-GSK3a (S21) ELISA - PEL-GSK3a-S21 from RayBiotech Category ELISA Kit Prices $481.00, $866.00, $1,924.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human GSK3a ELISA Kit - HG0271 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine GSK3a ELISA Kit - AG0271 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

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