| Gene Symbol |
ATP6V1C2
|
| Entrez Gene |
245973
|
| Alt Symbol |
ATP6C2, VMA5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
|
| Other Description |
V-ATPase C2 subunit|V-ATPase subunit C 2|V-type proton ATPase subunit C 2|vacuolar proton pump subunit C 2
|
| Swissprots |
Q96EL8 Q8NEY4
|
| Accessions |
AAY24069 EAX00951 EAX00952 Q8NEY4 AK127836 AK292952 BAF85641 AY039759 AAK83464 BC012142 AAH12142 BX358022 CD636943 DB230703 DQ892255 ABM83181 EU176679 ABW03480 XM_011510339 XP_011508641 XM_011510340 XP_011508642 XM_011510341 XP_011508643 XR_922657 XR_922658 XR_922659 XR_922660 XR_922661 XR_922662 XR_922663 XR_922664 NM_001039362 NP_001034451 NM_144583 NP_653184
|
| Function |
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
|
| Tissue Specificity |
Kidney and placenta. {ECO:0000269|PubMed:12384298}.
|
| Top Pathways |
Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis
|