Gene Symbol | ATP6V1C2 |
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Entrez Gene | 245973 |
Alt Symbol | ATP6C2, VMA5 |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 |
Other Description | V-ATPase C2 subunit|V-ATPase subunit C 2|V-type proton ATPase subunit C 2|vacuolar proton pump subunit C 2 |
Swissprots | Q96EL8 Q8NEY4 |
Accessions | AAY24069 EAX00951 EAX00952 Q8NEY4 AK127836 AK292952 BAF85641 AY039759 AAK83464 BC012142 AAH12142 BX358022 CD636943 DB230703 DQ892255 ABM83181 EU176679 ABW03480 XM_011510339 XP_011508641 XM_011510340 XP_011508642 XM_011510341 XP_011508643 XR_922657 XR_922658 XR_922659 XR_922660 XR_922661 XR_922662 XR_922663 XR_922664 NM_001039362 NP_001034451 NM_144583 NP_653184 |
Function | Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
Tissue Specificity | Kidney and placenta. {ECO:0000269|PubMed:12384298}. |
Top Pathways | Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis |
V-ATPase C2 CRISPR/Cas9 KO Plasmid (h) - sc-415172 from Santa Cruz Biotechnology
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V-ATPase C2 HDR Plasmid (h) - sc-415172-HDR from Santa Cruz Biotechnology
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V-ATPase C2 Double Nickase Plasmid (h) - sc-415172-NIC from Santa Cruz Biotechnology
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V-ATPase C2 Double Nickase Plasmid (h2) - sc-415172-NIC-2 from Santa Cruz Biotechnology
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V-ATPase C2 CRISPR Activation Plasmid (h) - sc-415172-ACT from Santa Cruz Biotechnology
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V-ATPase C2 CRISPR Activation Plasmid (h2) - sc-415172-ACT-2 from Santa Cruz Biotechnology
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V-ATPase C2 Lentiviral Activation Particles (h) - sc-415172-LAC from Santa Cruz Biotechnology
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V-ATPase C2 Lentiviral Activation Particles (h2) - sc-415172-LAC-2 from Santa Cruz Biotechnology
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V-ATPase C2 siRNA (h) - sc-63205 from Santa Cruz Biotechnology
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V-ATPase C2 shRNA Plasmid (h) - sc-63205-SH from Santa Cruz Biotechnology
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V-ATPase C2 shRNA (h) Lentiviral Particles - sc-63205-V from Santa Cruz Biotechnology
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ATP6V1C2 RNAi - H00245973-R02 from Novus Biologicals
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MISSION® esiRNA - EHU008091 from Sigma-Aldrich
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MISSION® esiRNA - EHU055591 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3730 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3730 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10467 from Sigma-Aldrich
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ATP6V1C2 siRNA (Human) - CRJ6614 from Cohesion Biosciences
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ATP6V1C2 RNAi - H00245973-R01 from Novus Biologicals
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ATP6V1C2 - MBS8219280 from MyBioSource
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shRNA set against Human ATP6V1C2 (NM_144583.3) - SHH243142 from Creative biogene
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shRNA set against Human ATP6V1C2(NM_144583.3) - SHG083851 from Creative biogene
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shRNA set against Human ATP6V1C2(NM_001039362.1) - SHG083915 from Creative biogene
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ATP6V1C2 shRNA Plasmid (Human) - CHJ6614 from Cohesion Biosciences
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ATP6V1C2 miRNA 3'UTR clone - MiUTR1H-00718 from Creative biogene
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