ABCB9

Gene Symbol	ABCB9
Entrez Gene	23457
Alt Symbol	EST122234, TAPL
Species	Human
Gene Type	protein-coding
Description	ATP-binding cassette, sub-family B (MDR/TAP), member 9
Other Description	ABC transporter 9 protein|ATP-binding cassette sub-family B member 9|TAP-like protein
Swissprots	Q96AB1 Q5W9G7 B4E2J0 Q9NP78 Q769F4 Q769F3 Q9P208
Accessions	CAI93387 CAI93388 EAW98353 EAW98354 EAW98355 EAW98356 EAW98357 EAW98358 EAW98359 EAW98360 EAW98361 EAW98362 EAW98363 Q9NP78 AB040953 BAA96044 AB045381 BAA97989 AB112582 BAC98409 AB112583 BAC98410 AB177852 BAD66830 AF216494 AAF89993 AK027624 BAG51360 AK074738 BAC11171 AK294225 BAG57529 AK304295 BAG65152 AL833963 CAD38811 BC017348 AAH17348 BC064384 AAH64384 CA503047 DA796102 U66676 XM_005253558 XP_005253615 XM_011538095 XP_011536397 XM_011538096 XP_011536398 XM_011538097 XP_011536399 XM_011538098 XP_011536400 XM_011538099 XP_011536401 XR_429086 XR_944513 NM_001243013 NP_001229942 NM_001243014 NP_001229943 NM_019624 NP_062570 NM_019625 NP_062571 NM_203444 NP_982269 NM_203445
Function	ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored. {ECO:0000269|PubMed:15863492, ECO:0000269|PubMed:17977821, ECO:0000269|PubMed:18434309}.
Subcellular Location	Lysosome membrane {ECO:0000269|PubMed:10748049, ECO:0000269|PubMed:15577206, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:17977821, ECO:0000269|PubMed:18175933, ECO:0000269|PubMed:18952056, ECO:0000269|PubMed:20377823, ECO:0000269|PubMed:21212514}; Multi- pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:10748049, ECO:0000269|PubMed:15577206, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:17977821, ECO:0000269|PubMed:18175933, ECO:0000269|PubMed:18952056, ECO:0000269|PubMed:20377823, ECO:0000269|PubMed:21212514}. Note=May be located in membrane rafts.
Tissue Specificity	Highly expressed in testis, and at moderate levels in brain, spinal cord, and thyroid. Not expressed in monocytes but strongly expressed during differentiation of monocytes to dendritic cells and macrophages. {ECO:0000269|PubMed:10748049, ECO:0000269|PubMed:17977821}.
Top Pathways	ABC transporters, Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ABCB9 peptide - ab45490 from Abcam Category Peptide Prices $181.00 Sizes 100 µg Species Human

Human ABCB9 protein fragment - ab161653 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

ABCB9 Antibody Blocking Peptide - LS-E16072 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ABCB9 Antibody Blocking Peptide - LS-E25464 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ABCB9 Protein - H00023457-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ABCB9 blocking peptide - GTX89769-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

ABCB9 Blocking Peptide - 33R-8059 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ABCB9 Peptide - AC21-0293-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ABCB9 - H00023457-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ABCB9 - H00023457-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ABCB9 Peptide - 45-180P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

ABCB9 fusion protein - Ag1542 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

ABCB9 fusion protein - ag0458 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ABCB9 fusion protein - ag9864 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human ABCB9, GST-tagged - ABCB9-9213H from Creative Biomart Category Protein Source E.coli Species Human

ABCB9/TAPL, Peptide - MBS426771 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

Recombinant ATP Binding Cassette Transporter B9 (ABCB9) - RPD639Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant ATP Binding Cassette Transporter B9 (ABCB9) - RPD639Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

ABCB9 Recombinant Protein Antigen - NBP1-84783PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ABCB9-Antibody-C-term-Blocking-Peptide - BP6115a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ABCB9 Peptide, Human - M34GP00048H from Creative Peptides Category Peptide Source Synthetic. Species Human

ABCB9 Recombinant Protein (OPCD00424) - OPCD00424 from Aviva Systems Biology Category Protein Source E.coli Species Human

ABCB9 Recombinant Protein Antigen - NBP2-55166PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Recombinant Human ABCB9 Protein, GST-Tagged - ABCB9-041H from Creative Biomart Category Protein Source Wheat Germ Species Human

Recombinant Human ABCB9 protein, His & T7-tagged - ABCB9-8131H from Creative Biomart Category Protein Source E. coli Species Human

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