ABCB9

Gene Symbol ABCB9
Entrez Gene 23457
Alt Symbol EST122234, TAPL
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family B (MDR/TAP), member 9
Other Description ABC transporter 9 protein|ATP-binding cassette sub-family B member 9|TAP-like protein
Swissprots Q96AB1 Q5W9G7 B4E2J0 Q9NP78 Q769F4 Q769F3 Q9P208
Accessions CAI93387 CAI93388 EAW98353 EAW98354 EAW98355 EAW98356 EAW98357 EAW98358 EAW98359 EAW98360 EAW98361 EAW98362 EAW98363 Q9NP78 AB040953 BAA96044 AB045381 BAA97989 AB112582 BAC98409 AB112583 BAC98410 AB177852 BAD66830 AF216494 AAF89993 AK027624 BAG51360 AK074738 BAC11171 AK294225 BAG57529 AK304295 BAG65152 AL833963 CAD38811 BC017348 AAH17348 BC064384 AAH64384 CA503047 DA796102 U66676 XM_005253558 XP_005253615 XM_011538095 XP_011536397 XM_011538096 XP_011536398 XM_011538097 XP_011536399 XM_011538098 XP_011536400 XM_011538099 XP_011536401 XR_429086 XR_944513 NM_001243013 NP_001229942 NM_001243014 NP_001229943 NM_019624 NP_062570 NM_019625 NP_062571 NM_203444 NP_982269 NM_203445
Function ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored. {ECO:0000269|PubMed:15863492, ECO:0000269|PubMed:17977821, ECO:0000269|PubMed:18434309}.
Subcellular Location Lysosome membrane {ECO:0000269|PubMed:10748049, ECO:0000269|PubMed:15577206, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:17977821, ECO:0000269|PubMed:18175933, ECO:0000269|PubMed:18952056, ECO:0000269|PubMed:20377823, ECO:0000269|PubMed:21212514}; Multi- pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:10748049, ECO:0000269|PubMed:15577206, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:17977821, ECO:0000269|PubMed:18175933, ECO:0000269|PubMed:18952056, ECO:0000269|PubMed:20377823, ECO:0000269|PubMed:21212514}. Note=May be located in membrane rafts.
Tissue Specificity Highly expressed in testis, and at moderate levels in brain, spinal cord, and thyroid. Not expressed in monocytes but strongly expressed during differentiation of monocytes to dendritic cells and macrophages. {ECO:0000269|PubMed:10748049, ECO:0000269|PubMed:17977821}.
Top Pathways ABC transporters, Lysosome

ABCB9 (A-8) - sc-393412 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ABCB9 (A-8): sc-393412. Western blot analysis of ABCB9 expression in HeLa (A) and NIH/3T3 (B) whole cell lysates.

ABCB9 (C-15) - sc-46745 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ABCB9 (C-15): sc-46745. Western blot analysis of ABCB9 expression in non-transfected 293T: sc-117752 (A), human ABCB9 transfected 293T: sc-116956 (B) and K-562 (C) whole cell lysates.

ABCB9 (E-2) - sc-393431 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ABCB9 (E-2): sc-393431. Western blot analysis of ABCB9 expression in NIH/3T3 whole cell lysate.

ABCB9 (H-300) - sc-366129 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ABCB9 (K-16) - sc-46746 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ABCB9 (K-16): sc-46746. Western blot analysis of ABCB9 expression in mouse thymus tissue extract.

ABCB9 (C-13) - sc-46744 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ABCB9 (C-13): sc-46744. Western blot analysis of ABCB9 expression in mouse thymus tissue extract.

Anti-ABCB9 antibody - ab86222 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human prostate carcinoma tissue labelling ABCB9 with ab86222 at 1/200 (1µg/ml). Detection: DAB.

Anti-ABCB9 antibody - ab39273 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-ABCB9 antibody (ab39273) + Nuclear cell lysate obtained from HeLa cells transfected with recombinant ABCB9SecondaryHRP-conjugated rabbit anti-goat IgGdeveloped using the ECL techniquePerformed under reducing conditions.This image is courtesy of an anonymous AbreviewSee Abreview

Anti-ABCB9 antibody - ab87531 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ABCB9 antibody (ab87531) at 1/2000 dilution + THP1 cell lysate at 60 µg

Anti-ABCB9 antibody - ab167259 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-ABCB9 antibody (ab167259) at 1 µg/mlLane 1 : ABCB9 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-ABCB9 antibody - Carboxyterminal end - ab60036 from Abcam

Prices $359.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ab60036 at 1/50 dilution staining ABCB9 in Human hepatocarcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. A peroxidase-conjugated secondary antibody was used, followed by AEC staining.

Anti-ABCB9 Antibody (aa752-766) - LS-C2977 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ABCB9 Antibody - LS-C306015 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ABCB9 Antibody - LS-C137427 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCB9 Antibody (aa482-581) - LS-C306023 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ABCB9 Antibody - LS-C309276 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ABCB9 Antibody (N-Terminus) - LS-C80604 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-ABCB9 Antibody (aa757-769) IHC-plus™ - LS-B2746 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-ABCB9 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2746 concentration 75 ug/ml.

Anti-ABCB9 Antibody (aa475-525) - LS-C286629 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse ABCB9 by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-ABCB9 used at a dilution of 1:100.

Anti-ABCB9 Antibody (aa475-525) - LS-C288754 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human ABCB9 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-ABCB9 used at a dilution of 1:200 (1 ug/ml).

ABCB9 Antibody - NBP1-18886 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ABCB9 Antibody [NBP1-18886] - Whole cell lysate from HeLa, 293T and mouse NIH3T3 cells.

ABCB9 Antibody - NB300-865 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

ABCB9 Antibody - NBP1-69513 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ABCB9 Antibody [NBP1-69513] - This Anti-ABCB9 antibody was used in Western Blot of Fetal Lung tissue lysate at a concentration of 1ug/ml.

ABCB9 Antibody - NBP1-84783 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: ABCB9 Antibody [NBP1-84783] - Staining of human liver shows moderate cytoplasmic and nucleolar positivity in hepatocytes.

ABCB9 Antibody - H00023457-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: ABCB9 Antibody [H00023457-D01P] - Analysis of ABCB9 expression in mouse kidney.
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