Gene Symbol |
FAM20C
|
Entrez Gene |
56975
|
Alt Symbol |
DMP-4, DMP4, GEF-CK, RNS
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
family with sequence similarity 20, member C
|
Other Description |
dentin matrix protein 4|extracellular serine/threonine protein kinase FAM20C|golgi-enriched fraction casein kinase
|
Swissprots |
Q5I0W9 L8B5W8 Q8IXL6 Q7Z4I0 Q9NPT2 A4D2Q5
|
Accessions |
EAL23705 EAW87149 EAW87150 EAW87151 EAW87152 EAW87153 EAW87154 EAW87155 EAW87156 EAW87157 Q8IXL6 AA135568 AB545605 BAM78534 AF533706 AAQ09019 AK026140 AK054704 AK125281 AL390137 AL390147 CAB99089 BC009531 BC040074 AAH40074 BC068086 BC087853 AAH87853 BQ026938 XM_011515457 XP_011513759 XR_242097 NM_020223 NP_064608
|
Function |
Calcium-binding kinase that phosphorylates the caseins and several secreted proteins implicated in biomineralization, including the secretory calcium binding phosphoproteins (SCPP). Preferencially phosphorylates its targets within the S-x-E/pS motif. {ECO:0000269|PubMed:22582013}.
|
Subcellular Location |
Secreted {ECO:0000250}.
|
Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:15676076}.
|