Gene Symbol | FAM20C |
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Entrez Gene | 56975 |
Alt Symbol | DMP-4, DMP4, GEF-CK, RNS |
Species | Human |
Gene Type | protein-coding |
Description | family with sequence similarity 20, member C |
Other Description | dentin matrix protein 4|extracellular serine/threonine protein kinase FAM20C|golgi-enriched fraction casein kinase |
Swissprots | Q5I0W9 L8B5W8 Q8IXL6 Q7Z4I0 Q9NPT2 A4D2Q5 |
Accessions | EAL23705 EAW87149 EAW87150 EAW87151 EAW87152 EAW87153 EAW87154 EAW87155 EAW87156 EAW87157 Q8IXL6 AA135568 AB545605 BAM78534 AF533706 AAQ09019 AK026140 AK054704 AK125281 AL390137 AL390147 CAB99089 BC009531 BC040074 AAH40074 BC068086 BC087853 AAH87853 BQ026938 XM_011515457 XP_011513759 XR_242097 NM_020223 NP_064608 |
Function | Calcium-binding kinase that phosphorylates the caseins and several secreted proteins implicated in biomineralization, including the secretory calcium binding phosphoproteins (SCPP). Preferencially phosphorylates its targets within the S-x-E/pS motif. {ECO:0000269|PubMed:22582013}. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:15676076}. |
FAM20C CRISPR/Cas9 KO Plasmid (h) - sc-406736 from Santa Cruz Biotechnology
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FAM20C HDR Plasmid (h) - sc-406736-HDR from Santa Cruz Biotechnology
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FAM20C Double Nickase Plasmid (h) - sc-406736-NIC from Santa Cruz Biotechnology
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FAM20C Double Nickase Plasmid (h2) - sc-406736-NIC-2 from Santa Cruz Biotechnology
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FAM20C CRISPR Activation Plasmid (h) - sc-406736-ACT from Santa Cruz Biotechnology
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FAM20C CRISPR Activation Plasmid (h2) - sc-406736-ACT-2 from Santa Cruz Biotechnology
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FAM20C Lentiviral Activation Particles (h) - sc-406736-LAC from Santa Cruz Biotechnology
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FAM20C Lentiviral Activation Particles (h2) - sc-406736-LAC-2 from Santa Cruz Biotechnology
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FAM20C siRNA (h) - sc-89666 from Santa Cruz Biotechnology
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FAM20C shRNA Plasmid (h) - sc-89666-SH from Santa Cruz Biotechnology
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FAM20C shRNA (h) Lentiviral Particles - sc-89666-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN8294 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8294 from Sigma-Aldrich
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FAM20C siRNA (Human) - CRJ1263 from Cohesion Biosciences
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FAM20C - MBS828130 from MyBioSource
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FAM20C CRISPR/Cas9 KO Plasmid (h2) - sc-406736-KO-2 from Santa Cruz Biotechnology
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FAM20C HDR Plasmid (h2) - sc-406736-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human FAM20C (NM_020223.3) - SHH290805 from Creative biogene
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Human FAM20C siRNA - orb271764 from Biorbyt
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FAM20C shRNA Plasmid (Human) - CHJ1263 from Cohesion Biosciences
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FAM20C miRNA 3'UTR clone - MiUTR3H-11635 from Creative biogene
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