| Gene Symbol |
RAB11FIP1
|
| Entrez Gene |
80223
|
| Alt Symbol |
NOEL1A, RCP, rab11-FIP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RAB11 family interacting protein 1 (class I)
|
| Other Description |
RAB11 coupling protein|Rab effector protein|Rab-interacting recycling protein|rab11 family-interacting protein 1
|
| Swissprots |
Q307T1 Q8TDL1 Q6WKZ4 Q6AZK4 Q6WKZ6 J3KNP0 Q6WKZ2 Q9H642 Q86YV4
|
| Accessions |
CAH25928 EAW63347 EAW63348 EAW63349 Q6WKZ4 AF368294 AAM09571 AK026177 AK026275 BAB15424 AK090437 BAC03418 AK092296 BAG52524 AK122583 BAC56924 AK124422 AK226111 AK291781 BAF84470 AL832155 AL833169 AY280966 AAQ18784 AY280967 AAQ18785 AY280968 AAQ18786 AY280969 AAQ18787 AY280970 AAQ18788 AY367050 AAR15506 BC001314 BC054881 BC077720 AAH77720 DQ083995 AAY86040 DQ236342 ABB43161 NM_001002233 NM_001002814 NP_001002814 NM_025151 NP_079427
|
| Function |
A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis. {ECO:0000269|PubMed:11786538, ECO:0000269|PubMed:15181150, ECO:0000269|PubMed:15355514, ECO:0000269|PubMed:16920206}.
|
| Subcellular Location |
Recycling endosome {ECO:0000269|PubMed:11786538, ECO:0000269|PubMed:15181150, ECO:0000269|PubMed:15280022, ECO:0000269|PubMed:15355514, ECO:0000269|PubMed:16920206}. Note=Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC).
|
| Tissue Specificity |
Isoform 2 is expressed in brain, heart, testis, lung, spleen, ovary and small intestine. {ECO:0000269|PubMed:11786538}.
|
| Top Pathways |
Endocytosis
|