Gene Symbol | RAB11FIP1 |
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Entrez Gene | 80223 |
Alt Symbol | NOEL1A, RCP, rab11-FIP1 |
Species | Human |
Gene Type | protein-coding |
Description | RAB11 family interacting protein 1 (class I) |
Other Description | RAB11 coupling protein|Rab effector protein|Rab-interacting recycling protein|rab11 family-interacting protein 1 |
Swissprots | Q307T1 Q8TDL1 Q6WKZ4 Q6AZK4 Q6WKZ6 J3KNP0 Q6WKZ2 Q9H642 Q86YV4 |
Accessions | CAH25928 EAW63347 EAW63348 EAW63349 Q6WKZ4 AF368294 AAM09571 AK026177 AK026275 BAB15424 AK090437 BAC03418 AK092296 BAG52524 AK122583 BAC56924 AK124422 AK226111 AK291781 BAF84470 AL832155 AL833169 AY280966 AAQ18784 AY280967 AAQ18785 AY280968 AAQ18786 AY280969 AAQ18787 AY280970 AAQ18788 AY367050 AAR15506 BC001314 BC054881 BC077720 AAH77720 DQ083995 AAY86040 DQ236342 ABB43161 NM_001002233 NM_001002814 NP_001002814 NM_025151 NP_079427 |
Function | A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis. {ECO:0000269|PubMed:11786538, ECO:0000269|PubMed:15181150, ECO:0000269|PubMed:15355514, ECO:0000269|PubMed:16920206}. |
Subcellular Location | Recycling endosome {ECO:0000269|PubMed:11786538, ECO:0000269|PubMed:15181150, ECO:0000269|PubMed:15280022, ECO:0000269|PubMed:15355514, ECO:0000269|PubMed:16920206}. Note=Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC). |
Tissue Specificity | Isoform 2 is expressed in brain, heart, testis, lung, spleen, ovary and small intestine. {ECO:0000269|PubMed:11786538}. |
Top Pathways | Endocytosis |
Rab11-FIP1 CRISPR/Cas9 KO Plasmid (h) - sc-407521 from Santa Cruz Biotechnology
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Rab11-FIP1 HDR Plasmid (h) - sc-407521-HDR from Santa Cruz Biotechnology
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Rab11-FIP1 Double Nickase Plasmid (h) - sc-407521-NIC from Santa Cruz Biotechnology
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Rab11-FIP1 Double Nickase Plasmid (h2) - sc-407521-NIC-2 from Santa Cruz Biotechnology
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Rab11-FIP1 CRISPR Activation Plasmid (h) - sc-407521-ACT from Santa Cruz Biotechnology
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Rab11-FIP1 CRISPR Activation Plasmid (h2) - sc-407521-ACT-2 from Santa Cruz Biotechnology
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Rab11-FIP1 Lentiviral Activation Particles (h) - sc-407521-LAC from Santa Cruz Biotechnology
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Rab11-FIP1 Lentiviral Activation Particles (h2) - sc-407521-LAC-2 from Santa Cruz Biotechnology
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Rab11-FIP1 siRNA (h) - sc-76331 from Santa Cruz Biotechnology
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Rab11-FIP1 shRNA Plasmid (h) - sc-76331-SH from Santa Cruz Biotechnology
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Rab11-FIP1 shRNA (h) Lentiviral Particles - sc-76331-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU062401 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17804 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17804 from Sigma-Aldrich
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RAB11FIP1 siRNA (Human) - CRJ2813 from Cohesion Biosciences
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RAB11FIP1 - MBS8221278 from MyBioSource
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shRNA set against Human RAB11FIP1 (NM_001002814.2) - SHH387844 from Creative biogene
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Human RAB11FIP1 siRNA - orb273314 from Biorbyt
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RAB11FIP1 shRNA Plasmid (Human) - CHJ2813 from Cohesion Biosciences
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RAB11FIP1 miRNA 3'UTR clone - MiUTR4H-TG07265 from Creative biogene
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