TIE1

Gene Symbol TIE1
Entrez Gene 7075
Alt Symbol JTK14, TIE
Species Human
Gene Type protein-coding
Description tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Other Description tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1|tyrosine-protein kinase receptor Tie-1
Swissprots P35590 B5A949 B5A950
Accessions AAD14299 CAK49654 CAK96151 EAX07106 EAX07107 P35590 AF217976 AAG17219 AK225560 AK296735 BAG59322 AK300399 BAG62130 AK300623 BAG62316 AK307639 AL833389 BC038239 AAH38239 BM970991 DB287371 EU826586 ACF47622 EU826587 ACF47623 EU826588 ACF47624 EU826589 ACF47625 EU826590 ACF47626 R13130 X60957 CAA43290 XM_005271163 XP_005271220 XM_005271164 XP_005271221 XM_006710869 XP_006710932 XR_946751 NM_001253357 NP_001240286 NM_005424 NP_005415
Function Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis. {ECO:0000269|PubMed:20227369}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15851516, ECO:0000269|PubMed:20227369}; Single-pass type I membrane protein {ECO:0000269|PubMed:15851516, ECO:0000269|PubMed:20227369}.
Tissue Specificity Specifically expressed in developing vascular endothelial cells.

Tie-1 (G-12) - sc-365961 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Tie-1 (G-12): sc-365961. Western blot analysis of Tie-1 expression in non-transfected: sc-117752 (A) and human Tie-1 transfected: sc-115397 (B) 293T whole cell lysates.

Tie-1 (G-18) - sc-31281 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Tie-1 (G-4) - sc-365257 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Tie-1 (G-4): sc-365257. Western blot analysis of Tie-1 expression in non-transfected: sc-117752 (A) and human Tie-1 transfected: sc-115397 (B) 293T whole cell lysates.

Tie-1 (H-180) - sc-9025 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Tie-1 (H-180): sc-9025. Western blot analysis of Tie-1 expression in PMA-induced K-562 (A), PMA-induced HL-60 (B) and ECV304 (C) whole cell lysates.

Tie-1 (S-20) - sc-31282 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Tie-1 (C-18) - sc-342 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Tie-1 (C-18): sc-342. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing membrane staining.

Tie-1 (12D9) - sc-101587 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Tie-1 (12D9): sc-101587. Western blot analysis of Tie-1 expression in non-transfected: sc-117752 (A) and human Tie-1 transfected: sc-115397 (B) 293T whole cell lysates.

Anti-TIE1 antibody - ab111354 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TIE1 antibody (ab111354) at 1/500 dilutionLane 1 : HepG2 cell extractLane 2 : K562 cell extractLane 3 : Jurkat cell extractLane 4 : Jurkat cell extract with immunizing peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-TIE1 antibody - ab64477 from Abcam

Prices $376.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
ab64477, at a dilution of 1/100, staining TIE1 in formalin fixed, paraffin embedded human tonsil tissue sections by Immunohistochemistry.

Anti-TIE1 antibody [8C9] - ab27851 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8C9
Overlay histogram showing K562 cells stained with ab27851 (red line). The cells were fixed with 80% methanol (5 min) and then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab27851, 1µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2µg/1x106 cells ) used under the same conditions. Acquisition of >5,000 events was performed. This antibody gave a positive signal in K562 cells fixed with 4% paraformaldehyde (10 min) used under the same conditions.Please note that Abcam do not have any data for use of this antibody on non-fixed cells. We welcome any customer feedback.

Anti-TIE1 antibody [8D12B10] - ab201977 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8D12B10
Anti-TIE1 antibody [8D12B10] (ab201977) at 1/500 dilution + human recombinant TIE1 protein

Anti-TIE1 antibody, prediluted - ab64488 from Abcam

Prices $376.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
ab64488, prediluted, staining TIE1 in formalin fixed, paraffin embedded human tonsil tissue by Immunohistochemistry.

Anti-TIE Antibody (aa12-42) - LS-C99141 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with TIE antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-TIE1 / TIE Antibody - LS-C10574 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-TIE1 / TIE Antibody - LS-C39691 from LifeSpan Bioscience

Prices $415.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TIE1 / TIE Antibody (C-Terminus, AP) - LS-C87128 from LifeSpan Bioscience

Prices $755.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TIE1 / TIE Antibody (N-Terminus, AP) - LS-C87129 from LifeSpan Bioscience

Prices $755.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TIE1 / TIE Antibody (clone 6F12) - LS-C194821 from LifeSpan Bioscience

Prices $665.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6F12

Anti-TIE1 / TIE Antibody (Extracellular Domain, clone 9C1) - LS-C193613 from LifeSpan Bioscience

Prices $905.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 9C1

Anti-TIE1 / TIE Antibody (Phe884) - LS-C193243 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TIE1 / TIE Antibody - LS-C194057 from LifeSpan Bioscience

Prices $905.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TIE1 / TIE Antibody (clone 8C9) - LS-C194822 from LifeSpan Bioscience

Prices $665.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8C9

Anti-TIE1 / TIE Antibody (aa361-389, APC) - LS-C271482 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIE1 / TIE Antibody (aa361-389, Biotin) - LS-C271484 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIE1 / TIE Antibody (aa361-389, FITC) - LS-C271485 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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