| Gene Symbol |
TIE1
|
| Entrez Gene |
7075
|
| Alt Symbol |
JTK14, TIE
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
|
| Other Description |
tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1|tyrosine-protein kinase receptor Tie-1
|
| Swissprots |
P35590 B5A949 B5A950
|
| Accessions |
AAD14299 CAK49654 CAK96151 EAX07106 EAX07107 P35590 AF217976 AAG17219 AK225560 AK296735 BAG59322 AK300399 BAG62130 AK300623 BAG62316 AK307639 AL833389 BC038239 AAH38239 BM970991 DB287371 EU826586 ACF47622 EU826587 ACF47623 EU826588 ACF47624 EU826589 ACF47625 EU826590 ACF47626 R13130 X60957 CAA43290 XM_005271163 XP_005271220 XM_005271164 XP_005271221 XM_006710869 XP_006710932 XR_946751 NM_001253357 NP_001240286 NM_005424 NP_005415
|
| Function |
Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis. {ECO:0000269|PubMed:20227369}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:15851516, ECO:0000269|PubMed:20227369}; Single-pass type I membrane protein {ECO:0000269|PubMed:15851516, ECO:0000269|PubMed:20227369}.
|
| Tissue Specificity |
Specifically expressed in developing vascular endothelial cells.
|