| Gene Symbol |
SUCLA2
|
| Entrez Gene |
8803
|
| Alt Symbol |
A-BETA, MTDPS5, SCS-betaA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
succinate-CoA ligase, ADP-forming, beta subunit
|
| Other Description |
ATP-specific succinyl-CoA synthetase subunit beta|ATP-specific succinyl-CoA synthetase, beta subunit|mitochondrial succinyl-CoA ligase [ADP-forming] subunit beta|renal carcinoma antigen NY-REN-39|succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial|succinyl-CoA synthetase beta-A chain
|
| Swissprots |
Q9NV21 Q5T9Q6 Q9NVP7 O95194 B2RDE7 Q9P2R7 Q5T9Q4
|
| Accessions |
ADP91734 ADP91735 ADP91736 ADP91737 ADP91738 ADP91739 ADP91740 ADP91741 ADP91742 ADP91743 ADP91744 ADP91745 ADP91746 ADP91747 ADP91748 ADP91749 ADP91750 ADP91751 ADP91752 ADP91753 ADP91754 ADP91755 ADP91756 ADP91757 ADP91758 ADP91759 ADP91760 ADP91761 ADP91762 ADP91763 ADP91764 ADP91765 ADP91766 ADP91767 ADP91768 ADP91769 ADP91770 ADP91771 ADP91772 ADP91773 EAX08775 EAX08776 EAX08777 EAX08778 Q9P2R7 AB035863 BAA92873 AF058953 AAC64396 AF087890 AAP97189 AK001458 BAA91703 AK001847 BAA91939 AK093506 AK225452 AK299437 BAG61414 AK302311 BAG63649 AK315513 BAG37894 AK316041 BAH14412 AK316271 BAH14642 AL080096 CAB45708 BC027587 AAH27587 BX640602 CAE45708 XM_011535292 XP_011533594 XM_011535293 XP_011533595 XR_941688 NM_003850 NP_003841
|
| Function |
Catalyzes the ATP-dependent ligation of succinate and CoA to form succinyl-CoA. {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion.
|
| Tissue Specificity |
Widely expressed. Not expressed in liver and lung. {ECO:0000269|PubMed:9765291}.
|
| Top Pathways |
Citrate cycle (TCA cycle), Carbon metabolism, Propanoate metabolism
|
![Western Blot: SUCLA2 Overexpression Lysate (Adult Normal) [NBL1-16594] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SUCLA2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2536_SUCLA2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16594-img0002.jpg)