SUCLA2

Gene Symbol SUCLA2
Entrez Gene 8803
Alt Symbol A-BETA, MTDPS5, SCS-betaA
Species Human
Gene Type protein-coding
Description succinate-CoA ligase, ADP-forming, beta subunit
Other Description ATP-specific succinyl-CoA synthetase subunit beta|ATP-specific succinyl-CoA synthetase, beta subunit|mitochondrial succinyl-CoA ligase [ADP-forming] subunit beta|renal carcinoma antigen NY-REN-39|succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial|succinyl-CoA synthetase beta-A chain
Swissprots Q9NV21 Q5T9Q6 Q9NVP7 O95194 B2RDE7 Q9P2R7 Q5T9Q4
Accessions ADP91734 ADP91735 ADP91736 ADP91737 ADP91738 ADP91739 ADP91740 ADP91741 ADP91742 ADP91743 ADP91744 ADP91745 ADP91746 ADP91747 ADP91748 ADP91749 ADP91750 ADP91751 ADP91752 ADP91753 ADP91754 ADP91755 ADP91756 ADP91757 ADP91758 ADP91759 ADP91760 ADP91761 ADP91762 ADP91763 ADP91764 ADP91765 ADP91766 ADP91767 ADP91768 ADP91769 ADP91770 ADP91771 ADP91772 ADP91773 EAX08775 EAX08776 EAX08777 EAX08778 Q9P2R7 AB035863 BAA92873 AF058953 AAC64396 AF087890 AAP97189 AK001458 BAA91703 AK001847 BAA91939 AK093506 AK225452 AK299437 BAG61414 AK302311 BAG63649 AK315513 BAG37894 AK316041 BAH14412 AK316271 BAH14642 AL080096 CAB45708 BC027587 AAH27587 BX640602 CAE45708 XM_011535292 XP_011533594 XM_011535293 XP_011533595 XR_941688 NM_003850 NP_003841
Function Catalyzes the ATP-dependent ligation of succinate and CoA to form succinyl-CoA. {ECO:0000250}.
Subcellular Location Mitochondrion.
Tissue Specificity Widely expressed. Not expressed in liver and lung. {ECO:0000269|PubMed:9765291}.
Top Pathways Citrate cycle (TCA cycle), Carbon metabolism, Propanoate metabolism

SUCLA2 (A-12) - sc-373926 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SUCLA2 (A-12): sc-373926. Western blot analysis of SUCLA2 expression in Hep G2 (A) and MOLT-4 (B) whole cell lysates.

SUCLA2 (A-9) - sc-374107 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SUCLA2 (A-9): sc-374107. Western blot analysis of SUCLA2 expression in 293T (A) and ES-2 (B) whole cell lysates.

SUCLA2 (C-19) - sc-79112 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

SUCLA2 (F-2) - sc-373959 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SUCLA2 (F-2): sc-373959. Western blot analysis of SUCLA2 expression in TT (A) and ES-2 (B) whole cell lysates.

SUCLA2 (G-17) - sc-79114 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
SUCLA2 (G-17): sc-79114. Western blot analysis of SUCLA2 expression in Hep G2 (A) and MOLT-4 (B) whole cell lysates.

SUCLA2 (H-296) - sc-68912 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SUCLA2 (H-296): sc-68912. Western blot analysis of SUCLA2 expression in Hep G2 (A) and MOLT-4 (B) whole cell lysates.

SUCLA2 (K-15) - sc-79115 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-SUCLA2 antibody - ab190845 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SUCLA2 antibody (ab190845) at 1 µg/mlLane 1 : Heart (Human) Tissue Lysate - adult normal tissue (ab29431)Lane 2 : Human Heart Mitochondrial LysateLane 3 : Heart (Mouse) Tissue LysateLane 4 : Liver (Mouse) Tissue LysateLane 5 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLane 6 : MOLT4 (Human acute lymphoblastic leukemia cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-SUCLA2 antibody - ab133956 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
IHC image of SUCLA2 staining in Human normal heartmuscle formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval (EDTA based pH 9.0 solution, epitope retrieval solution 2) for 20 mins. The section was then incubated with ab133956, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-SUCLA2 antibody - ab97868 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SUCLA2 antibody (ab97868) at 1/1000 dilutionLane 1 : HepG2 whole cell lysateLane 2 : Molt-4 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-SUCLA2 antibody [EPR14925] - ab183513 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14925
Western blot analysis of HepG2 cell lysate immunoprecipitated using ab183513 at 1/50 dilution. Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG secondary antibody used at 1/1500 dilution.

Anti-SUCLA2 Antibody (aa289-338) - LS-C151787 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SUCLA2 antibody Western Blot of Fetal Heart.

Anti-SUCLA2 Antibody (aa115-164) - LS-C151788 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SUCLA2 antibody Western Blot of Fetal Heart.

Anti-SUCLA2 Antibody (aa138-416) - LS-C186095 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Cal27 xenograft using SUCLA2 antibody at 1:500 dilution.

SUCLA2 Antibody - NBP1-33015 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SUCLA2 Antibody [NBP1-33015] -  A: Hep G2 B: Molt-4.

SUCLA2 Antibody - NBP1-85860 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SUCLA2 Antibody [NBP1-85860] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10 Lane 2: Mouse Cerebral Cortex tissue

Anti-SUCLA2 antibody produced in rabbit - HPA039435 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SUCLA2: <B>Cat. No. HPA039435</B>: Immunohistochemical staining of human stomach shows cytoplasmic positivity in glandular cells.

Anti-SUCLA2 antibody produced in rabbit - SAB2702040 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SUCLA2: <B>Cat. No. SAB2702040</B>: Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using SUCLA2 antibody at a 1:500 dilution.

Anti-SUCLA2 (16-27) antibody produced in rabbit - SAB1100644 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysates of Hep-G2 (lane 1) and Jurkat (lane 2) cells were separated on SDS-PAGE, blotted with Anti-SUCLA2 (16-27) (<B>Cat. No. SAB1100644</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500 <BR/>2. Antibody dilution 1:500

Anti-SUCLA2 (291-305) antibody produced in rabbit - SAB1100645 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-SUCLA2 (291-305) : <B>Cat. No. SAB1100645</B>: Immunofluorescence of HUVEC cells using SUCLA2 (291-305) , Cat. No. SAB1100645 (red) at a 1:100 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

SUCLA2 antibody - C-terminal region (ARP64675_P050) - ARP64675_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SUCLA2 antibody - N-terminal region (ARP64676_P050) - ARP64676_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SUCLA2 antibody - orb74212 from Biorbyt

Prices $723.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Western Blot analysis of A:HepG2, B:Molt-4 whole cell lysate using SUCLA2 antibody

SUCLA2 antibody - 70R-20636 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

SUCLA2 antibody (OAGA00790) - OAGA00790 from Aviva Systems Biology

Prices $340.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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