Gene Symbol |
YLPM1
|
Entrez Gene |
56252
|
Alt Symbol |
C14orf170, PPP1R169, ZAP113, ZAP3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
YLP motif containing 1
|
Other Description |
YLP motif-containing protein 1|nuclear protein ZAP3|protein phosphatase 1, regulatory subunit 169
|
Swissprots |
Q96I64 Q9P1V7 P49752 P49750
|
Accessions |
AAF61275 P49750 AK090435 BAC03416 AK095760 AK096592 AK297582 BAG59971 AL832365 BC007792 AAH07792 BC023570 AAH23570 BC044636 AAH44636 BC172585 AAI72585 BX102033 BX647164 DB096717 L40396 L40400 AAC42006 L40403 AAC42008 XM_005267860 XP_005267917 XM_011536966 XP_011535268 XM_011536967 XP_011535269 XR_943494 NM_019589 NP_062535
|
Function |
Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation. {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000269|PubMed:17890166}. Nucleus speckle {ECO:0000250}. Note=Migrates to nucleolar caps upon blockage of transcription.
|
Tissue Specificity |
Expressed in neuronal, neuroblastoma and embryonic kidney cell lines (at protein level). {ECO:0000269|PubMed:17890166}.
|